LINC02434

Summary

LINC02434 (long intergenic non-protein coding RNA 2434, HGNC:53365) is a long non-coding RNA gene on chromosome 4q35.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53365
Approved symbol	LINC02434
Name	long intergenic non-protein coding RNA 2434
Location	4q35.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248370
Ensembl biotype	lncRNA
Entrez	105377606
RNAcentral	URS00026A262F — lncRNA, 823 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 27 — 27 lncRNA

ENST00000502419, ENST00000658544, ENST00000658558, ENST00000660215, ENST00000660255, ENST00000661756, ENST00000662356, ENST00000663042, ENST00000663842, ENST00000666556, ENST00000667086, ENST00000759581, ENST00000759582, ENST00000759583, ENST00000759584, ENST00000759585, ENST00000759586, ENST00000759587, ENST00000759588, ENST00000759589, ENST00000759590, ENST00000759591, ENST00000759592, ENST00000759593, ENST00000759594, ENST00000759595, ENST00000759596

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502419 — 2 exons

Exon	Start	End
ENSE00004112411	188160501	188161140
ENSE00004112438	188159862	188160102

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 86.01.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1216 / max 16.2041, expressed in 36 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
50933	0.0906	35
50934	0.0311	19

Top tissues by expression

53 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.01	gold quality
placenta	UBERON:0001987	66.32	gold quality
testis	UBERON:0000473	64.06	gold quality
right testis	UBERON:0004534	63.77	gold quality
left testis	UBERON:0004533	63.40	gold quality
liver	UBERON:0002107	58.41	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.75	gold quality
uterine cervix	UBERON:0000002	57.73	silver quality
prefrontal cortex	UBERON:0000451	53.04	silver quality
tonsil	UBERON:0002372	52.65	silver quality
multicellular organism	UBERON:0000468	52.47	gold quality
kidney	UBERON:0002113	49.63	gold quality
blood	UBERON:0000178	48.43	gold quality
hypothalamus	UBERON:0001898	47.84	gold quality
monocyte	CL:0000576	47.79	silver quality
islet of Langerhans	UBERON:0000006	47.60	gold quality
putamen	UBERON:0001874	46.69	gold quality
muscle of leg	UBERON:0001383	46.54	gold quality
thoracic mammary gland	UBERON:0005200	46.16	gold quality
gastrocnemius	UBERON:0001388	45.36	gold quality
right lobe of liver	UBERON:0001114	45.16	silver quality
heart left ventricle	UBERON:0002084	45.01	gold quality
subcutaneous adipose tissue	UBERON:0002190	44.02	silver quality
right atrium auricular region	UBERON:0006631	43.77	gold quality
adrenal gland	UBERON:0002369	43.75	silver quality
lung	UBERON:0002048	43.04	gold quality
adipose tissue	UBERON:0001013	42.86	gold quality
left adrenal gland	UBERON:0001234	42.64	silver quality
cerebral cortex	UBERON:0000956	42.48	silver quality
amygdala	UBERON:0001876	42.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.