LINC02443

Summary

LINC02443 (long intergenic non-protein coding RNA 2443, HGNC:53375) is a long non-coding RNA gene on chromosome 12p13.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53375
Approved symbol	LINC02443
Name	long intergenic non-protein coding RNA 2443
Location	12p13.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256115
Ensembl biotype	lncRNA
Entrez	101929584
RNAcentral	URS00007E36BF — lncRNA, 848 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 42 — 42 lncRNA

ENST00000536518, ENST00000540237, ENST00000540619, ENST00000544717, ENST00000652862, ENST00000654414, ENST00000654905, ENST00000655694, ENST00000660094, ENST00000662631, ENST00000663953, ENST00000664597, ENST00000669073, ENST00000669681, ENST00000671564, ENST00000790117, ENST00000790118, ENST00000790119, ENST00000790120, ENST00000790121, ENST00000790122, ENST00000790123, ENST00000790124, ENST00000790125, ENST00000790126, ENST00000790127, ENST00000790128, ENST00000790129, ENST00000790130, ENST00000790131, ENST00000790132, ENST00000790133, ENST00000790134, ENST00000790135, ENST00000790136, ENST00000790137, ENST00000790138, ENST00000790139, ENST00000790140, ENST00000790141, ENST00000790142, ENST00000790143

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000536518 — 4 exons

Exon	Start	End
ENSE00002268885	5239888	5240112
ENSE00004170054	5243068	5243281
ENSE00004170088	5244101	5244184
ENSE00004170097	5238041	5238323

Expression profiles

Bgee: expression breadth broad, 60 present calls, max score 82.80.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0058 / max 6.7663, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
129030	0.0058	3

Top tissues by expression

171 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	82.80	gold quality
right testis	UBERON:0004534	80.83	gold quality
left testis	UBERON:0004533	80.46	gold quality
testis	UBERON:0000473	77.48	gold quality
colonic epithelium	UBERON:0000397	66.84	silver quality
endothelial cell	CL:0000115	66.75	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.64	gold quality
superficial temporal artery	UBERON:0001614	59.71	gold quality
uterine cervix	UBERON:0000002	55.66	gold quality
mucosa of paranasal sinus	UBERON:0005030	54.61	gold quality
monocyte	CL:0000576	53.44	silver quality
upper leg skin	UBERON:0004262	52.93	silver quality
cardia of stomach	UBERON:0001162	51.67	gold quality
gastrocnemius	UBERON:0001388	50.85	gold quality
ectocervix	UBERON:0012249	50.42	gold quality
heart left ventricle	UBERON:0002084	50.26	silver quality
oocyte	CL:0000023	49.84	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.48	gold quality
cardiac ventricle	UBERON:0002082	48.86	silver quality
right frontal lobe	UBERON:0002810	48.41	gold quality
body of pancreas	UBERON:0001150	48.28	gold quality
adult organism	UBERON:0007023	46.41	silver quality
lower esophagus muscularis layer	UBERON:0035833	46.22	gold quality
anatomical system	UBERON:0000467	45.58	gold quality
esophagus	UBERON:0001043	45.49	silver quality
material anatomical entity	UBERON:0000465	45.32	gold quality
multicellular organism	UBERON:0000468	45.23	gold quality
ventral tegmental area	UBERON:0002691	44.53	gold quality
placenta	UBERON:0001987	44.22	gold quality
substantia nigra pars reticulata	UBERON:0001966	43.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.