LINC02445

Summary

LINC02445 (long intergenic non-protein coding RNA 2445, HGNC:53377) is a long non-coding RNA gene on chromosome 12q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53377
Approved symbol	LINC02445
Name	long intergenic non-protein coding RNA 2445
Location	12q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257750
Ensembl biotype	lncRNA
Entrez	105369840
RNAcentral	URS0000EF585B — lncRNA, 495 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000551387, ENST00000664550, ENST00000809336, ENST00000809337, ENST00000809338, ENST00000809339, ENST00000809340

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000551387 — 5 exons

Exon	Start	End
ENSE00002352325	73796098	73796160
ENSE00002352775	73771586	73771727
ENSE00002361681	73760689	73760760
ENSE00002380953	73767616	73767747
ENSE00002384362	73798678	73798727

Expression profiles

Bgee: expression breadth broad, 46 present calls, max score 84.76.

Top tissues by expression

46 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.76	gold quality
left testis	UBERON:0004533	61.58	gold quality
testis	UBERON:0000473	61.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.37	gold quality
right testis	UBERON:0004534	60.28	gold quality
cortex of kidney	UBERON:0001225	59.73	gold quality
monocyte	CL:0000576	59.26	gold quality
placenta	UBERON:0001987	58.44	gold quality
blood	UBERON:0000178	53.99	gold quality
gall bladder	UBERON:0002110	53.77	gold quality
multicellular organism	UBERON:0000468	53.50	gold quality
gastrocnemius	UBERON:0001388	52.81	gold quality
corpus callosum	UBERON:0002336	52.80	gold quality
prefrontal cortex	UBERON:0000451	47.83	silver quality
Brodmann (1909) area 9	UBERON:0013540	47.44	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	47.11	gold quality
amygdala	UBERON:0001876	46.29	gold quality
tibial nerve	UBERON:0001323	45.83	gold quality
esophagus mucosa	UBERON:0002469	45.29	silver quality
right lobe of liver	UBERON:0001114	44.75	silver quality
stomach	UBERON:0000945	44.63	silver quality
substantia nigra	UBERON:0002038	44.50	gold quality
brain	UBERON:0000955	44.06	gold quality
anterior cingulate cortex	UBERON:0009835	43.63	gold quality
Ammon’s horn	UBERON:0001954	43.54	gold quality
putamen	UBERON:0001874	43.28	gold quality
omental fat pad	UBERON:0010414	43.21	gold quality
body of stomach	UBERON:0001161	42.91	silver quality
hypothalamus	UBERON:0001898	42.55	gold quality
lower esophagus muscularis layer	UBERON:0035833	42.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.