LINC02447

Summary

LINC02447 (long intergenic non-protein coding RNA 2447, HGNC:53379) is a long non-coding RNA gene on chromosome 4p16.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53379
Approved symbol	LINC02447
Name	long intergenic non-protein coding RNA 2447
Location	4p16.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245468
Ensembl biotype	lncRNA
Entrez	730971
RNAcentral	URS000075C91B — lncRNA, 2140 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000499242, ENST00000501888, ENST00000504402, ENST00000663544, ENST00000803907, ENST00000803908, ENST00000803909

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499242 — 2 exons

Exon	Start	End
ENSE00004194798	7098068	7099454
ENSE00004194808	7103268	7103408

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 83.11.

FANTOM5 (CAGE): breadth broad, TPM avg 1.0289 / max 15.3369, expressed in 596 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
51280	1.0289	596

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	83.11	gold quality
colonic epithelium	UBERON:0000397	82.33	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.33	silver quality
left testis	UBERON:0004533	74.09	gold quality
testis	UBERON:0000473	73.61	gold quality
right testis	UBERON:0004534	73.21	gold quality
body of pancreas	UBERON:0001150	72.53	gold quality
pancreas	UBERON:0001264	71.90	gold quality
stromal cell of endometrium	CL:0002255	71.15	gold quality
islet of Langerhans	UBERON:0000006	70.61	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.07	gold quality
adult mammalian kidney	UBERON:0000082	67.96	gold quality
pituitary gland	UBERON:0000007	66.60	gold quality
adenohypophysis	UBERON:0002196	66.54	gold quality
fundus of stomach	UBERON:0001160	65.85	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	65.68	gold quality
kidney	UBERON:0002113	65.48	gold quality
calcaneal tendon	UBERON:0003701	65.29	gold quality
skeletal muscle tissue	UBERON:0001134	65.25	gold quality
muscle tissue	UBERON:0002385	65.14	gold quality
left adrenal gland cortex	UBERON:0035825	65.02	gold quality
muscle of leg	UBERON:0001383	64.64	gold quality
gastrocnemius	UBERON:0001388	64.53	gold quality
body of stomach	UBERON:0001161	64.45	gold quality
heart left ventricle	UBERON:0002084	64.32	gold quality
substantia nigra	UBERON:0002038	64.21	gold quality
left adrenal gland	UBERON:0001234	63.96	gold quality
heart	UBERON:0000948	63.83	gold quality
right atrium auricular region	UBERON:0006631	63.82	gold quality
putamen	UBERON:0001874	63.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.