LINC02448

Summary

LINC02448 (long intergenic non-protein coding RNA 2448, HGNC:53380) is a long non-coding RNA gene on chromosome 12q14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53380
Approved symbol	LINC02448
Name	long intergenic non-protein coding RNA 2448
Location	12q14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257230
Ensembl biotype	lncRNA
Entrez	105369792
RNAcentral	URS0002A22D6C — lncRNA, 876 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000548613, ENST00000719152, ENST00000719153, ENST00000719154, ENST00000719155, ENST00000719156, ENST00000719157

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000548613 — 3 exons

Exon	Start	End
ENSE00002359835	59523278	59523455
ENSE00002364960	59523703	59523983
ENSE00002398904	59524061	59524184

Expression profiles

Bgee: expression breadth broad, 55 present calls, max score 95.88.

Top tissues by expression

55 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.88	gold quality
lower esophagus mucosa	UBERON:0035834	61.03	gold quality
corpus callosum	UBERON:0002336	59.23	gold quality
blood	UBERON:0000178	58.48	gold quality
left ovary	UBERON:0002119	58.02	gold quality
monocyte	CL:0000576	55.98	gold quality
tonsil	UBERON:0002372	55.56	gold quality
esophagus mucosa	UBERON:0002469	54.90	gold quality
esophagus	UBERON:0001043	54.56	gold quality
minor salivary gland	UBERON:0001830	53.92	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.77	gold quality
sural nerve	UBERON:0015488	53.15	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	51.69	gold quality
calcaneal tendon	UBERON:0003701	51.49	silver quality
prefrontal cortex	UBERON:0000451	51.42	gold quality
heart left ventricle	UBERON:0002084	50.74	gold quality
superior frontal gyrus	UBERON:0002661	50.27	gold quality
fundus of stomach	UBERON:0001160	48.59	gold quality
primary visual cortex	UBERON:0002436	48.51	silver quality
ectocervix	UBERON:0012249	47.67	gold quality
vagina	UBERON:0000996	47.62	gold quality
stomach	UBERON:0000945	46.73	gold quality
tibial nerve	UBERON:0001323	46.58	silver quality
lower esophagus	UBERON:0013473	45.42	gold quality
skin of abdomen	UBERON:0001416	45.39	gold quality
body of pancreas	UBERON:0001150	44.96	silver quality
left adrenal gland cortex	UBERON:0035825	44.86	gold quality
right testis	UBERON:0004534	44.60	gold quality
testis	UBERON:0000473	44.37	gold quality
gastrocnemius	UBERON:0001388	44.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.