LINC02449

Summary

LINC02449 (long intergenic non-protein coding RNA 2449, HGNC:53381) is a long non-coding RNA gene on chromosome 12p13.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53381
Approved symbol	LINC02449
Name	long intergenic non-protein coding RNA 2449
Location	12p13.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000215241
Ensembl biotype	lncRNA
Entrez	101927905
RNAcentral	URS000075E951 — lncRNA, 966 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 105 — 105 lncRNA

ENST00000304751, ENST00000399866, ENST00000535746, ENST00000536034, ENST00000537764, ENST00000539795, ENST00000666548, ENST00000669735, ENST00000735593, ENST00000735594, ENST00000735595, ENST00000735596, ENST00000735597, ENST00000735598, ENST00000735599, ENST00000735600, ENST00000735601, ENST00000735602, ENST00000735603, ENST00000735604, ENST00000735605, ENST00000735606, ENST00000735607, ENST00000735608, ENST00000735609, ENST00000735610, ENST00000735611, ENST00000735612, ENST00000735613, ENST00000735614, ENST00000735615, ENST00000735616, ENST00000735617, ENST00000735618, ENST00000735619, ENST00000735620, ENST00000735621, ENST00000735622, ENST00000735623, ENST00000735624, ENST00000735625, ENST00000735626, ENST00000735627, ENST00000735628, ENST00000735629, ENST00000735630, ENST00000735631, ENST00000735632, ENST00000735633, ENST00000735634, ENST00000735635, ENST00000735636, ENST00000735637, ENST00000735638, ENST00000735639, ENST00000735640, ENST00000735641, ENST00000735642, ENST00000735643, ENST00000735644, ENST00000735645, ENST00000735646, ENST00000735647, ENST00000735648, ENST00000735649, ENST00000735650, ENST00000735651, ENST00000735652, ENST00000735653, ENST00000735654, ENST00000735655, ENST00000735656, ENST00000735657, ENST00000735658, ENST00000735659, ENST00000735660, ENST00000735661, ENST00000735662, ENST00000735663, ENST00000735664, ENST00000735665, ENST00000735666, ENST00000735667, ENST00000735668, ENST00000735669, ENST00000735670, ENST00000735671, ENST00000735672, ENST00000735673, ENST00000735674, ENST00000735675, ENST00000735676, ENST00000735678, ENST00000735681, ENST00000735683, ENST00000735684, ENST00000735685, ENST00000735686, ENST00000735687, ENST00000735688, ENST00000735689, ENST00000735690, ENST00000735691, ENST00000735997, ENST00000735998

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000304751 — 2 exons

Exon	Start	End
ENSE00002213221	8235415	8235999
ENSE00002245172	8238737	8238946

Expression profiles

Bgee: expression breadth ubiquitous, 135 present calls, max score 90.65.

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	90.65	gold quality
right uterine tube	UBERON:0001302	90.52	gold quality
cortical plate	UBERON:0005343	87.92	gold quality
cerebellar vermis	UBERON:0004720	87.50	gold quality
pituitary gland	UBERON:0000007	87.29	gold quality
nucleus accumbens	UBERON:0001882	86.73	gold quality
adenohypophysis	UBERON:0002196	86.16	gold quality
right hemisphere of cerebellum	UBERON:0014890	85.60	gold quality
cerebellum	UBERON:0002037	84.99	gold quality
cerebellar cortex	UBERON:0002129	84.97	gold quality
cerebellar hemisphere	UBERON:0002245	84.95	gold quality
superior frontal gyrus	UBERON:0002661	84.75	gold quality
caudate nucleus	UBERON:0001873	84.31	gold quality
right frontal lobe	UBERON:0002810	84.16	gold quality
primary visual cortex	UBERON:0002436	83.93	gold quality
brain	UBERON:0000955	83.81	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.61	gold quality
putamen	UBERON:0001874	83.49	gold quality
hypothalamus	UBERON:0001898	83.39	gold quality
frontal cortex	UBERON:0001870	83.09	gold quality
cerebral cortex	UBERON:0000956	82.84	gold quality
anterior cingulate cortex	UBERON:0009835	82.78	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	82.66	gold quality
temporal lobe	UBERON:0001871	82.61	gold quality
amygdala	UBERON:0001876	82.56	gold quality
Ammon’s horn	UBERON:0001954	82.54	gold quality
left ovary	UBERON:0002119	82.19	gold quality
prefrontal cortex	UBERON:0000451	82.18	gold quality
Brodmann (1909) area 9	UBERON:0013540	81.64	gold quality
ovary	UBERON:0000992	81.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.87

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.