LINC02450

Summary

LINC02450 (long intergenic non-protein coding RNA 2450, HGNC:53382) is a long non-coding RNA gene on chromosome 12q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53382
Approved symbol	LINC02450
Name	long intergenic non-protein coding RNA 2450
Location	12q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257114
Ensembl biotype	lncRNA
Entrez	105369739
RNAcentral	URS0000A776DD — lncRNA, 1007 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000546982, ENST00000548764, ENST00000550177, ENST00000655248, ENST00000655825, ENST00000660010, ENST00000660815, ENST00000662561, ENST00000667161, ENST00000715727, ENST00000761458, ENST00000761459, ENST00000761460, ENST00000761461, ENST00000761462, ENST00000761463, ENST00000761464, ENST00000761465

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000546982 — 5 exons

Exon	Start	End
ENSE00002343461	42686612	42686701
ENSE00002347168	42652460	42652583
ENSE00002350920	42681922	42682063
ENSE00002377645	42647103	42647239
ENSE00002409585	42646583	42646654

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 85.09.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1180 / max 11.3908, expressed in 49 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
125113	0.1180	49

Top tissues by expression

200 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pancreatic ductal cell	CL:0002079	85.09	silver quality
sperm	CL:0000019	79.52	silver quality
cardiac muscle of right atrium	UBERON:0003379	78.96	gold quality
left ventricle myocardium	UBERON:0006566	78.93	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.69	gold quality
kidney epithelium	UBERON:0004819	77.22	gold quality
tibialis anterior	UBERON:0001385	76.50	silver quality
upper arm skin	UBERON:0004263	75.06	gold quality
superficial temporal artery	UBERON:0001614	74.28	gold quality
myocardium	UBERON:0002349	70.74	gold quality
mucosa of paranasal sinus	UBERON:0005030	69.30	gold quality
nasal cavity epithelium	UBERON:0005384	68.69	gold quality
amniotic fluid	UBERON:0000173	67.86	gold quality
germinal epithelium of ovary	UBERON:0001304	66.57	gold quality
deltoid	UBERON:0001476	65.34	silver quality
parietal pleura	UBERON:0002400	63.42	gold quality
visceral pleura	UBERON:0002401	63.38	gold quality
quadriceps femoris	UBERON:0001377	63.31	gold quality
palpebral conjunctiva	UBERON:0001812	62.91	gold quality
gingival epithelium	UBERON:0001949	62.51	gold quality
secondary oocyte	CL:0000655	62.40	gold quality
upper leg skin	UBERON:0004262	62.01	gold quality
vastus lateralis	UBERON:0001379	61.66	gold quality
ileal mucosa	UBERON:0000331	60.69	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	60.54	gold quality
muscle tissue	UBERON:0002385	60.19	gold quality
heart right ventricle	UBERON:0002080	59.54	gold quality
tibia	UBERON:0000979	59.16	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.75	gold quality
layer of synovial tissue	UBERON:0007616	57.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.