LINC02456

Summary

LINC02456 (long intergenic non-protein coding RNA 2456, HGNC:53389) is a long non-coding RNA gene on chromosome 12q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53389
Approved symbol	LINC02456
Name	long intergenic non-protein coding RNA 2456
Location	12q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000283052
Ensembl biotype	lncRNA
Entrez	105369942
RNAcentral	URS0002617F2D — lncRNA, 1940 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000635615, ENST00000704346, ENST00000827586, ENST00000833832

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000635615 — 6 exons

Exon	Start	End
ENSE00003784408	102423071	102423180
ENSE00003786339	102304632	102304756
ENSE00003786749	102462728	102463491
ENSE00003787493	102348883	102348932
ENSE00003787817	102315311	102315490
ENSE00003789132	102304355	102304448

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 81.66.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.66	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.83	gold quality
tonsil	UBERON:0002372	68.72	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.78	gold quality
bone marrow cell	CL:0002092	65.37	silver quality
skeletal muscle tissue	UBERON:0001134	62.23	silver quality
liver	UBERON:0002107	57.48	gold quality
endometrium	UBERON:0001295	57.00	gold quality
small intestine	UBERON:0002108	54.50	gold quality
calcaneal tendon	UBERON:0003701	54.37	gold quality
cortex of kidney	UBERON:0001225	54.23	gold quality
blood	UBERON:0000178	53.68	silver quality
leukocyte	CL:0000738	53.44	silver quality
right lobe of liver	UBERON:0001114	52.27	gold quality
lymph node	UBERON:0000029	49.81	gold quality
smooth muscle tissue	UBERON:0001135	49.61	gold quality
body of pancreas	UBERON:0001150	49.48	gold quality
placenta	UBERON:0001987	49.07	gold quality
prefrontal cortex	UBERON:0000451	48.86	gold quality
urinary bladder	UBERON:0001255	48.76	gold quality
adrenal gland	UBERON:0002369	48.65	silver quality
monocyte	CL:0000576	48.23	silver quality
islet of Langerhans	UBERON:0000006	47.98	silver quality
muscle of leg	UBERON:0001383	47.90	gold quality
left testis	UBERON:0004533	47.78	gold quality
testis	UBERON:0000473	47.50	gold quality
multicellular organism	UBERON:0000468	46.82	gold quality
gastrocnemius	UBERON:0001388	46.76	silver quality
lung	UBERON:0002048	46.25	gold quality
vermiform appendix	UBERON:0001154	46.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.52

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.