LINC02459

Summary

LINC02459 (long intergenic non-protein coding RNA 2459, HGNC:53395) is a long non-coding RNA gene on chromosome 12q24.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53395
Approved symbol	LINC02459
Name	long intergenic non-protein coding RNA 2459
Location	12q24.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257476
Ensembl biotype	lncRNA
Entrez	105369996
RNAcentral	URS0000BC43C0 — lncRNA, 473 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000551761

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000551761 — 2 exons

Exon	Start	End
ENSE00004211884	114238473	114239400
ENSE00004211885	114241728	114241954

Expression profiles

Bgee: expression breadth broad, 30 present calls, max score 63.81.

Top tissues by expression

30 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	63.81	silver quality
left testis	UBERON:0004533	63.42	gold quality
testis	UBERON:0000473	63.04	gold quality
right testis	UBERON:0004534	60.91	gold quality
multicellular organism	UBERON:0000468	59.37	gold quality
monocyte	CL:0000576	57.20	gold quality
placenta	UBERON:0001987	54.56	gold quality
tibial nerve	UBERON:0001323	51.53	gold quality
right lobe of liver	UBERON:0001114	50.29	gold quality
gastrocnemius	UBERON:0001388	49.00	gold quality
heart left ventricle	UBERON:0002084	47.73	gold quality
prostate gland	UBERON:0002367	46.59	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	45.25	gold quality
thyroid gland	UBERON:0002046	43.96	silver quality
lower esophagus muscularis layer	UBERON:0035833	43.63	silver quality
right atrium auricular region	UBERON:0006631	42.95	silver quality
nucleus accumbens	UBERON:0001882	42.03	silver quality
muscle layer of sigmoid colon	UBERON:0035805	40.35	silver quality
omental fat pad	UBERON:0010414	40.01	silver quality
transverse colon	UBERON:0001157	39.96	silver quality
esophagus mucosa	UBERON:0002469	39.52	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	38.47	silver quality
vagina	UBERON:0000996	38.21	silver quality
left adrenal gland	UBERON:0001234	37.98	silver quality
tibial artery	UBERON:0007610	37.88	silver quality
putamen	UBERON:0001874	37.86	silver quality
ascending aorta	UBERON:0001496	37.75	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	37.66	silver quality
subcutaneous adipose tissue	UBERON:0002190	37.11	silver quality
left lobe of thyroid gland	UBERON:0001120	35.67	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.