LINC02466

Summary

LINC02466 (long intergenic non-protein coding RNA 2466, HGNC:53405) is a long non-coding RNA gene on chromosome 4q28.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53405
Approved symbol	LINC02466
Name	long intergenic non-protein coding RNA 2466
Location	4q28.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246876
Ensembl biotype	lncRNA
Entrez	101927282
RNAcentral	URS000075DE62 — lncRNA, 1978 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 25 — 25 lncRNA

ENST00000500092, ENST00000509105, ENST00000653323, ENST00000653915, ENST00000654715, ENST00000660846, ENST00000663942, ENST00000664709, ENST00000665329, ENST00000667892, ENST00000669328, ENST00000670512, ENST00000830548, ENST00000830549, ENST00000830550, ENST00000830551, ENST00000830552, ENST00000830553, ENST00000830554, ENST00000830555, ENST00000830556, ENST00000830557, ENST00000830558, ENST00000830559, ENST00000830560

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500092 — 5 exons

Exon	Start	End
ENSE00001969694	129749628	129749720
ENSE00001970770	129726922	129727033
ENSE00001983903	129744308	129744379
ENSE00001990663	129724171	129725789
ENSE00002020270	129771412	129771481

Expression profiles

Bgee: expression breadth broad, 43 present calls, max score 79.56.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0050 / max 6.7663, expressed in 2 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
53932	0.0050	2

Top tissues by expression

161 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.56	gold quality
left testis	UBERON:0004533	71.10	gold quality
right testis	UBERON:0004534	70.67	gold quality
testis	UBERON:0000473	68.52	gold quality
sperm	CL:0000019	58.92	silver quality
monocyte	CL:0000576	52.54	gold quality
cortex of kidney	UBERON:0001225	49.20	gold quality
left adrenal gland	UBERON:0001234	47.50	gold quality
prefrontal cortex	UBERON:0000451	47.28	silver quality
gastrocnemius	UBERON:0001388	47.28	gold quality
islet of Langerhans	UBERON:0000006	46.59	gold quality
right lobe of liver	UBERON:0001114	45.16	silver quality
upper lobe of lung	UBERON:0008948	44.75	silver quality
tibial artery	UBERON:0007610	44.52	silver quality
lower lobe of lung	UBERON:0008949	44.47	silver quality
anatomical system	UBERON:0000467	44.02	gold quality
material anatomical entity	UBERON:0000465	43.76	gold quality
multicellular organism	UBERON:0000468	43.73	gold quality
aorta	UBERON:0000947	43.61	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
cerebellar hemisphere	UBERON:0002245	42.79	silver quality
secondary oocyte	CL:0000655	42.57	gold quality
adrenal gland	UBERON:0002369	42.10	silver quality
Brodmann (1909) area 9	UBERON:0013540	41.72	silver quality
right hemisphere of cerebellum	UBERON:0014890	41.66	silver quality
kidney	UBERON:0002113	41.64	gold quality
duodenum	UBERON:0002114	41.44	silver quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.92

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.