LINC02469

Summary

LINC02469 (long intergenic non-protein coding RNA 2469, HGNC:53408) is a long non-coding RNA gene on chromosome 4q21.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53408
Approved symbol	LINC02469
Name	long intergenic non-protein coding RNA 2469
Location	4q21.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248408
Ensembl biotype	lncRNA
Entrez	105377301
RNAcentral	URS00005911AD — lncRNA, 741 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000506460

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506460 — 4 exons

Exon	Start	End
ENSE00002032330	79667989	79668127
ENSE00002052933	79696413	79696837
ENSE00002061356	79689988	79690076
ENSE00002079728	79663761	79663848

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 78.99.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0089 / max 11.6085, expressed in 2 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
48502	0.0037	2
48503	0.0028	1
48501	0.0024	1

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.99	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.52	gold quality
prostate gland	UBERON:0002367	74.32	gold quality
colonic epithelium	UBERON:0000397	69.85	gold quality
bone marrow cell	CL:0002092	66.51	silver quality
ventricular zone	UBERON:0003053	63.54	gold quality
sural nerve	UBERON:0015488	61.94	gold quality
skeletal muscle tissue	UBERON:0001134	61.51	gold quality
subcutaneous adipose tissue	UBERON:0002190	61.44	gold quality
mucosa of transverse colon	UBERON:0004991	60.60	gold quality
liver	UBERON:0002107	60.24	gold quality
ganglionic eminence	UBERON:0004023	59.05	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.81	gold quality
blood	UBERON:0000178	58.41	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.39	gold quality
adipose tissue	UBERON:0001013	58.01	gold quality
leukocyte	CL:0000738	58.00	gold quality
adult mammalian kidney	UBERON:0000082	57.63	gold quality
cortex of kidney	UBERON:0001225	57.47	gold quality
kidney	UBERON:0002113	57.46	gold quality
bone marrow	UBERON:0002371	56.64	silver quality
right coronary artery	UBERON:0001625	56.07	gold quality
monocyte	CL:0000576	55.81	gold quality
tibial artery	UBERON:0007610	55.36	gold quality
popliteal artery	UBERON:0002250	55.33	gold quality
right lobe of liver	UBERON:0001114	55.14	gold quality
left coronary artery	UBERON:0001626	54.62	gold quality
metanephros cortex	UBERON:0010533	54.57	gold quality
omental fat pad	UBERON:0010414	53.84	gold quality
calcaneal tendon	UBERON:0003701	53.12	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.