LINC02487

Summary

LINC02487 (long intergenic non-protein coding RNA 2487, HGNC:53466) is a long non-coding RNA gene on chromosome 6q27.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53466
Approved symbol	LINC02487
Name	long intergenic non-protein coding RNA 2487
Location	6q27
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000203688
Ensembl biotype	lncRNA
Entrez	441178
RNAcentral	URS00021ED9EC — lncRNA, 2251 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 26 — 26 lncRNA

ENST00000400831, ENST00000644320, ENST00000654811, ENST00000667387, ENST00000732235, ENST00000732236, ENST00000732237, ENST00000732238, ENST00000732239, ENST00000732240, ENST00000732241, ENST00000732242, ENST00000732243, ENST00000732244, ENST00000732245, ENST00000732246, ENST00000732247, ENST00000732248, ENST00000732249, ENST00000732250, ENST00000732251, ENST00000732252, ENST00000732253, ENST00000732254, ENST00000732255, ENST00000732256

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000400831 — 4 exons

Exon	Start	End
ENSE00001600132	167683108	167683169
ENSE00001609695	167682333	167682447
ENSE00001612490	167679626	167681937
ENSE00001686406	167683720	167683787

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 99.17.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1622 / max 67.5184, expressed in 25 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
76716	0.1622	25

Top tissues by expression

214 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lower esophagus mucosa	UBERON:0035834	99.17	gold quality
esophagus mucosa	UBERON:0002469	94.24	gold quality
oral cavity	UBERON:0000167	90.15	gold quality
pharyngeal mucosa	UBERON:0000355	89.61	gold quality
esophagus squamous epithelium	UBERON:0006920	89.43	gold quality
buccal mucosa cell	CL:0002336	83.34	gold quality
esophagus	UBERON:0001043	81.07	gold quality
tonsil	UBERON:0002372	80.84	gold quality
gingiva	UBERON:0001828	80.66	gold quality
gingival epithelium	UBERON:0001949	80.36	silver quality
amniotic fluid	UBERON:0000173	79.56	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.64	silver quality
vagina	UBERON:0000996	75.15	gold quality
sural nerve	UBERON:0015488	73.88	silver quality
ganglionic eminence	UBERON:0004023	72.90	gold quality
body of tongue	UBERON:0011876	71.26	gold quality
superior surface of tongue	UBERON:0007371	69.56	gold quality
tongue	UBERON:0001723	69.29	gold quality
parotid gland	UBERON:0001831	67.45	gold quality
myocardium	UBERON:0002349	67.45	gold quality
cortical plate	UBERON:0005343	67.27	gold quality
mouth mucosa	UBERON:0003729	66.87	gold quality
vastus lateralis	UBERON:0001379	64.75	gold quality
quadriceps femoris	UBERON:0001377	64.68	gold quality
nasal cavity epithelium	UBERON:0005384	64.22	gold quality
minor salivary gland	UBERON:0001830	63.96	gold quality
ventricular zone	UBERON:0003053	63.81	gold quality
mammary duct	UBERON:0001765	63.74	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	63.40	gold quality
saliva-secreting gland	UBERON:0001044	63.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.29

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Tumor Suppressor LINC02487 Inhibits the Progression of Cervical Cancer in Vitro by Regulating the PTEN/Akt/mTOR Pathway. (PMID:39190388)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.