LINC02489

Summary

LINC02489 (long intergenic non-protein coding RNA 2489, HGNC:53470) is a long non-coding RNA gene on chromosome 11p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53470
Approved symbol	LINC02489
Name	long intergenic non-protein coding RNA 2489
Location	11p11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	CTD-2589M5.4
Ensembl gene	ENSG00000255007
Ensembl biotype	lncRNA
Entrez	101928919
RNAcentral	URS00026A1BA8 — lncRNA, 1859 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000527239, ENST00000686099, ENST00000785059, ENST00000785060, ENST00000785061, ENST00000785062, ENST00000785063, ENST00000785064, ENST00000785065

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000527239 — 2 exons

Exon	Start	End
ENSE00004160463	46256270	46256541
ENSE00004160478	46274381	46274678

Expression profiles

Bgee: expression breadth ubiquitous, 110 present calls, max score 93.79.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3867 / max 234.7378, expressed in 61 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
119505	0.3867	61

Top tissues by expression

110 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pituitary gland	UBERON:0000007	93.79	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	92.79	gold quality
adenohypophysis	UBERON:0002196	91.15	gold quality
body of pancreas	UBERON:0001150	75.52	gold quality
body of stomach	UBERON:0001161	75.13	gold quality
right lung	UBERON:0002167	75.01	gold quality
pancreas	UBERON:0001264	73.29	gold quality
stomach	UBERON:0000945	73.23	gold quality
tonsil	UBERON:0002372	69.29	gold quality
smooth muscle tissue	UBERON:0001135	68.92	gold quality
minor salivary gland	UBERON:0001830	68.87	gold quality
saliva-secreting gland	UBERON:0001044	68.84	gold quality
muscle tissue	UBERON:0002385	68.78	gold quality
islet of Langerhans	UBERON:0000006	68.14	gold quality
lung	UBERON:0002048	68.06	gold quality
fundus of stomach	UBERON:0001160	67.95	gold quality
upper lobe of left lung	UBERON:0008952	67.64	gold quality
mucosa of transverse colon	UBERON:0004991	67.53	gold quality
duodenum	UBERON:0002114	66.13	gold quality
rectum	UBERON:0001052	66.06	gold quality
urinary bladder	UBERON:0001255	66.02	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	65.39	gold quality
monocyte	CL:0000576	65.25	gold quality
prostate gland	UBERON:0002367	65.07	gold quality
gall bladder	UBERON:0002110	65.03	gold quality
placenta	UBERON:0001987	63.73	gold quality
myometrium	UBERON:0001296	62.93	gold quality
cortex of kidney	UBERON:0001225	62.79	gold quality
prefrontal cortex	UBERON:0000451	61.06	gold quality
right adrenal gland cortex	UBERON:0035827	60.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	10.41

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.