LINC02490

Summary

LINC02490 (long intergenic non-protein coding RNA 2490, HGNC:53471) is a long non-coding RNA gene on chromosome 15q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53471
Approved symbol	LINC02490
Name	long intergenic non-protein coding RNA 2490
Location	15q21.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-209E8
Ensembl gene	ENSG00000259237
Ensembl biotype	lncRNA
Entrez	105370822
RNAcentral	URS000052DC2C — lncRNA, 601 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000559915, ENST00000692805, ENST00000780970, ENST00000780971, ENST00000780972, ENST00000780973, ENST00000780974, ENST00000780975, ENST00000780976, ENST00000780977, ENST00000780978, ENST00000780979, ENST00000780980, ENST00000780981, ENST00000780982, ENST00000780983, ENST00000780984, ENST00000780985, ENST00000780986, ENST00000780987, ENST00000780988, ENST00000780989, ENST00000780990, ENST00000780991, ENST00000780992, ENST00000780993, ENST00000780994, ENST00000780995, ENST00000780996

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000559915 — 3 exons

Exon	Start	End
ENSE00002552982	53118219	53118265
ENSE00004152696	53129239	53130349
ENSE00004152708	53116362	53116458

Expression profiles

Bgee: expression breadth broad, 82 present calls, max score 69.31.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0491 / max 11.5103, expressed in 14 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
146729	0.0439	11
146728	0.0051	3

Top tissues by expression

82 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ventricular zone	UBERON:0003053	69.31	gold quality
rectum	UBERON:0001052	65.21	gold quality
duodenum	UBERON:0002114	64.77	gold quality
gall bladder	UBERON:0002110	64.16	gold quality
transverse colon	UBERON:0001157	61.56	gold quality
mucosa of transverse colon	UBERON:0004991	60.69	gold quality
colon	UBERON:0001155	59.26	gold quality
liver	UBERON:0002107	58.72	gold quality
intestine	UBERON:0000160	58.25	gold quality
body of pancreas	UBERON:0001150	56.33	gold quality
right lobe of liver	UBERON:0001114	56.26	gold quality
monocyte	CL:0000576	55.73	gold quality
islet of Langerhans	UBERON:0000006	55.69	gold quality
small intestine	UBERON:0002108	54.67	gold quality
small intestine Peyer’s patch	UBERON:0003454	53.14	gold quality
prefrontal cortex	UBERON:0000451	51.63	gold quality
calcaneal tendon	UBERON:0003701	51.32	silver quality
blood	UBERON:0000178	50.44	silver quality
multicellular organism	UBERON:0000468	49.62	gold quality
heart left ventricle	UBERON:0002084	49.57	gold quality
vermiform appendix	UBERON:0001154	49.52	gold quality
muscle layer of sigmoid colon	UBERON:0035805	48.84	gold quality
urinary bladder	UBERON:0001255	47.37	gold quality
heart	UBERON:0000948	47.33	gold quality
left uterine tube	UBERON:0001303	46.97	gold quality
tibial artery	UBERON:0007610	46.34	gold quality
gastrocnemius	UBERON:0001388	46.11	silver quality
right atrium auricular region	UBERON:0006631	45.11	gold quality
right hemisphere of cerebellum	UBERON:0014890	44.82	silver quality
adult mammalian kidney	UBERON:0000082	44.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.