LINC02491

Summary

LINC02491 (long intergenic non-protein coding RNA 2491, HGNC:53475) is a long non-coding RNA gene on chromosome 4q31.21.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53475
Approved symbol	LINC02491
Name	long intergenic non-protein coding RNA 2491
Location	4q31.21
Locus type	RNA, long non-coding
Status	Approved
Entrez	105377467
RNAcentral	URS00026A1C6A — lncRNA, 789 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000042680 (4:145598463 T>C), RS1000561056 (4:145598744 T>C), RS1001017727 (4:145598157 A>G), RS1001045671 (4:145597770 G>A,T), RS1001151641 (4:145598426 A>C), RS1002141520 (4:145597720 T>C), RS1002169571 (4:145597485 T>C), RS1003027809 (4:145600758 C>T), RS1003058910 (4:145600518 C>G), RS1003446914 (4:145602728 C>T), RS1004155720 (4:145600776 G>T), RS1005669904 (4:145597656 G>A), RS1005897678 (4:145602037 G>C), RS1005968190 (4:145597412 A>G), RS1006043230 (4:145601475 T>G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.