LINC02492

Summary

LINC02492 (long intergenic non-protein coding RNA 2492, HGNC:53476) is a long non-coding RNA gene on chromosome 4q35.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53476
Approved symbol	LINC02492
Name	long intergenic non-protein coding RNA 2492
Location	4q35.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250590
Ensembl biotype	lncRNA
Entrez	100506272
RNAcentral	URS00004AEE93 — lncRNA, 483 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 35 — 35 lncRNA

ENST00000502952, ENST00000507817, ENST00000514767, ENST00000515660, ENST00000653020, ENST00000654552, ENST00000654776, ENST00000656713, ENST00000656759, ENST00000657902, ENST00000658590, ENST00000659431, ENST00000663188, ENST00000664977, ENST00000665640, ENST00000667027, ENST00000667508, ENST00000667648, ENST00000668469, ENST00000669092, ENST00000735969, ENST00000735970, ENST00000735971, ENST00000735972, ENST00000735973, ENST00000735974, ENST00000735975, ENST00000735976, ENST00000735977, ENST00000735978, ENST00000735979, ENST00000735980, ENST00000735981, ENST00000735982, ENST00000735983

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502952 — 5 exons

Exon	Start	End
ENSE00002025280	187557747	187557920
ENSE00002033739	187558077	187558264
ENSE00002036254	187592884	187592927
ENSE00002063173	187582421	187582530
ENSE00002064845	187555911	187555958

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 87.67.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0579 / max 4.5718, expressed in 30 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55399	0.0322	20
55391	0.0258	10

Top tissues by expression

160 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.67	gold quality
buccal mucosa cell	CL:0002336	83.10	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.80	gold quality
left testis	UBERON:0004533	73.73	gold quality
right testis	UBERON:0004534	72.48	gold quality
testis	UBERON:0000473	71.85	gold quality
ganglionic eminence	UBERON:0004023	65.50	gold quality
sperm	CL:0000019	62.87	silver quality
monocyte	CL:0000576	57.01	gold quality
vena cava	UBERON:0004087	56.74	gold quality
lateral nuclear group of thalamus	UBERON:0002736	56.41	gold quality
nasal cavity epithelium	UBERON:0005384	54.56	gold quality
tibial nerve	UBERON:0001323	54.40	gold quality
islet of Langerhans	UBERON:0000006	52.33	gold quality
gastrocnemius	UBERON:0001388	51.11	gold quality
muscle layer of sigmoid colon	UBERON:0035805	49.09	gold quality
ovary	UBERON:0000992	47.60	silver quality
tendon of biceps brachii	UBERON:0008188	45.35	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.05	gold quality
anatomical system	UBERON:0000467	44.80	gold quality
Brodmann (1909) area 9	UBERON:0013540	44.72	gold quality
prefrontal cortex	UBERON:0000451	44.59	gold quality
material anatomical entity	UBERON:0000465	44.57	gold quality
multicellular organism	UBERON:0000468	44.54	gold quality
nasal cavity mucosa	UBERON:0001826	44.43	gold quality
amniotic fluid	UBERON:0000173	43.70	gold quality
tendon	UBERON:0000043	43.51	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	43.12	gold quality
dorsal plus ventral thalamus	UBERON:0001897	43.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.