LINC02498

Summary

LINC02498 (long intergenic non-protein coding RNA 2498, HGNC:53483) is a long non-coding RNA gene on chromosome 4p16.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53483
Approved symbol	LINC02498
Name	long intergenic non-protein coding RNA 2498
Location	4p16.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000283083
Ensembl biotype	lncRNA
Entrez	102723525
RNAcentral	URS0002A228DB — lncRNA, 1217 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000635390, ENST00000720785, ENST00000720786, ENST00000720787, ENST00000720788, ENST00000720789, ENST00000720790, ENST00000720791, ENST00000720792, ENST00000720793, ENST00000720794, ENST00000720795

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000635390 — 3 exons

Exon	Start	End
ENSE00003789688	10738106	10738549
ENSE00004039895	10737553	10737777
ENSE00004039914	10749172	10749592

Expression profiles

Bgee: expression breadth broad, 28 present calls, max score 95.13.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0336 / max 33.3803, expressed in 7 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
46921	0.0282	7
46920	0.0054	3

Top tissues by expression

43 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.13	gold quality
bone marrow	UBERON:0002371	89.38	silver quality
pancreas	UBERON:0001264	86.35	silver quality
skeletal muscle tissue	UBERON:0001134	85.42	silver quality
liver	UBERON:0002107	84.93	silver quality
lung	UBERON:0002048	82.88	silver quality
spinal cord	UBERON:0002240	82.52	silver quality
heart	UBERON:0000948	81.90	silver quality
spleen	UBERON:0002106	81.16	silver quality
subcutaneous adipose tissue	UBERON:0002190	80.42	silver quality
thymus	UBERON:0002370	79.81	silver quality
left testis	UBERON:0004533	74.39	gold quality
testis	UBERON:0000473	74.16	gold quality
right testis	UBERON:0004534	72.23	gold quality
adipose tissue	UBERON:0001013	70.65	silver quality
quadriceps femoris	UBERON:0001377	65.49	gold quality
multicellular organism	UBERON:0000468	65.03	gold quality
caudate nucleus	UBERON:0001873	64.91	gold quality
cerebellar vermis	UBERON:0004720	64.61	gold quality
anterior cingulate cortex	UBERON:0009835	63.76	gold quality
monocyte	CL:0000576	60.42	gold quality
prefrontal cortex	UBERON:0000451	53.53	gold quality
blood	UBERON:0000178	51.86	silver quality
tibial nerve	UBERON:0001323	51.19	gold quality
gastrocnemius	UBERON:0001388	49.77	gold quality
hindlimb stylopod muscle	UBERON:0004252	49.61	silver quality
frontal cortex	UBERON:0001870	48.32	silver quality
cortex of kidney	UBERON:0001225	46.75	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	45.79	silver quality
adenohypophysis	UBERON:0002196	45.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.