LINC02517

Summary

LINC02517 (long intergenic non-protein coding RNA 2517, HGNC:53506) is a long non-coding RNA gene on chromosome 4p16.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53506
Approved symbol	LINC02517
Name	long intergenic non-protein coding RNA 2517
Location	4p16.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249145
Ensembl biotype	lncRNA
Entrez	105374374
RNAcentral	URS0000BC448D — lncRNA, 788 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 30 — 30 lncRNA

ENST00000503186, ENST00000509453, ENST00000646635, ENST00000653648, ENST00000657733, ENST00000657851, ENST00000658537, ENST00000660291, ENST00000661538, ENST00000661956, ENST00000671202, ENST00000690289, ENST00000692221, ENST00000700929, ENST00000701442, ENST00000701523, ENST00000829910, ENST00000829911, ENST00000829912, ENST00000829913, ENST00000829914, ENST00000829915, ENST00000829916, ENST00000829917, ENST00000829918, ENST00000829919, ENST00000829920, ENST00000829921, ENST00000829922, ENST00000829923

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503186 — 5 exons

Exon	Start	End
ENSE00002039114	8322126	8322243
ENSE00002048761	8320281	8320522
ENSE00002087372	8321957	8322032
ENSE00003985992	8323719	8323965
ENSE00004243822	8320117	8320168

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 92.64.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0442 / max 19.3038, expressed in 11 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
46880	0.0200	8
46881	0.0164	8
203103	0.0047	3
46879	0.0031	2

Top tissues by expression

217 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
apex of heart	UBERON:0002098	92.64	gold quality
heart left ventricle	UBERON:0002084	86.87	gold quality
cardiac ventricle	UBERON:0002082	86.42	gold quality
right atrium auricular region	UBERON:0006631	83.48	gold quality
heart	UBERON:0000948	82.99	gold quality
cardiac atrium	UBERON:0002081	82.76	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.39	gold quality
myocardium	UBERON:0002349	80.06	silver quality
heart right ventricle	UBERON:0002080	78.33	gold quality
cardiac muscle of right atrium	UBERON:0003379	77.83	gold quality
gingival epithelium	UBERON:0001949	71.57	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	68.68	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.84	gold quality
cortical plate	UBERON:0005343	67.55	gold quality
gingiva	UBERON:0001828	66.48	gold quality
sperm	CL:0000019	65.93	gold quality
upper arm skin	UBERON:0004263	65.49	gold quality
calcaneal tendon	UBERON:0003701	64.97	gold quality
secondary oocyte	CL:0000655	63.12	gold quality
stromal cell of endometrium	CL:0002255	62.70	gold quality
deltoid	UBERON:0001476	61.41	gold quality
tibialis anterior	UBERON:0001385	61.09	silver quality
pancreatic ductal cell	CL:0002079	60.86	silver quality
muscle of leg	UBERON:0001383	60.71	gold quality
skeletal muscle tissue	UBERON:0001134	60.65	gold quality
vena cava	UBERON:0004087	60.58	gold quality
esophagus squamous epithelium	UBERON:0006920	60.11	gold quality
gastrocnemius	UBERON:0001388	59.97	gold quality
ganglionic eminence	UBERON:0004023	59.95	gold quality
ventricular zone	UBERON:0003053	59.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.17

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.