LINC02518

Summary

LINC02518 (long intergenic non-protein coding RNA 2518, HGNC:53509) is a long non-coding RNA gene on chromosome 6q21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53509
Approved symbol	LINC02518
Name	long intergenic non-protein coding RNA 2518
Location	6q21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232316
Ensembl biotype	lncRNA
Entrez	105377957
RNAcentral	URS0000BC45D4 — lncRNA, 550 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000421737, ENST00000430728, ENST00000656121, ENST00000835060, ENST00000835061, ENST00000835062, ENST00000835248, ENST00000835249, ENST00000835250, ENST00000835251, ENST00000835252, ENST00000835253, ENST00000835254

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421737 — 6 exons

Exon	Start	End
ENSE00004253565	113441421	113441455
ENSE00004253569	113433337	113433447
ENSE00004253577	113428540	113428978
ENSE00004253583	113433601	113433730
ENSE00004253584	113435376	113435510
ENSE00004253587	113434410	113434495

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 81.27.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0680 / max 13.2299, expressed in 31 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
75174	0.0451	17
75175	0.0228	8

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.27	gold quality
calcaneal tendon	UBERON:0003701	78.03	gold quality
skin of abdomen	UBERON:0001416	72.58	gold quality
placenta	UBERON:0001987	70.56	gold quality
zone of skin	UBERON:0000014	69.09	gold quality
prostate gland	UBERON:0002367	67.98	gold quality
urinary bladder	UBERON:0001255	66.55	gold quality
skin of leg	UBERON:0001511	66.55	gold quality
ganglionic eminence	UBERON:0004023	65.89	gold quality
skeletal muscle tissue	UBERON:0001134	64.35	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.35	gold quality
stromal cell of endometrium	CL:0002255	61.88	gold quality
monocyte	CL:0000576	61.85	gold quality
body of pancreas	UBERON:0001150	61.48	gold quality
pancreas	UBERON:0001264	60.89	gold quality
lymph node	UBERON:0000029	60.88	gold quality
popliteal artery	UBERON:0002250	57.77	gold quality
tibial artery	UBERON:0007610	57.77	gold quality
gall bladder	UBERON:0002110	57.71	gold quality
right coronary artery	UBERON:0001625	57.37	gold quality
liver	UBERON:0002107	56.98	gold quality
islet of Langerhans	UBERON:0000006	56.26	gold quality
bone marrow	UBERON:0002371	55.77	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.69	gold quality
endometrium	UBERON:0001295	55.64	gold quality
tonsil	UBERON:0002372	55.35	gold quality
blood	UBERON:0000178	55.29	gold quality
muscle of leg	UBERON:0001383	55.24	gold quality
right lung	UBERON:0002167	55.02	gold quality
thoracic mammary gland	UBERON:0005200	54.53	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.