LINC02531

Summary

LINC02531 (long intergenic non-protein coding RNA 2531, HGNC:53557) is a long non-coding RNA gene on chromosome 6q16.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53557
Approved symbol	LINC02531
Name	long intergenic non-protein coding RNA 2531
Location	6q16.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000220908
Ensembl biotype	lncRNA
Entrez	105377896, 107986533
RNAcentral	URS0002853B5A — lncRNA, 4667 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000404689, ENST00000661503, ENST00000799047, ENST00000799048, ENST00000799049

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000404689 — 4 exons

Exon	Start	End
ENSE00001790770	92723003	92723087
ENSE00004187257	92588925	92589332
ENSE00004187261	92633506	92633601
ENSE00004187262	92723322	92723829

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 89.47.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0568 / max 14.9415, expressed in 21 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
74755	0.0249	12
74753	0.0181	8
74754	0.0138	6

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.47	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.61	gold quality
sural nerve	UBERON:0015488	70.26	gold quality
lower esophagus mucosa	UBERON:0035834	61.25	gold quality
skeletal muscle tissue	UBERON:0001134	61.18	gold quality
ganglionic eminence	UBERON:0004023	60.22	gold quality
cortex of kidney	UBERON:0001225	59.85	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.50	gold quality
muscle of leg	UBERON:0001383	56.56	gold quality
lymph node	UBERON:0000029	55.80	gold quality
islet of Langerhans	UBERON:0000006	55.06	gold quality
gastrocnemius	UBERON:0001388	54.93	gold quality
apex of heart	UBERON:0002098	54.54	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.34	gold quality
blood	UBERON:0000178	53.06	gold quality
ectocervix	UBERON:0012249	52.83	gold quality
gall bladder	UBERON:0002110	52.60	gold quality
placenta	UBERON:0001987	52.52	gold quality
monocyte	CL:0000576	51.57	silver quality
duodenum	UBERON:0002114	51.29	gold quality
bone marrow	UBERON:0002371	51.26	silver quality
prefrontal cortex	UBERON:0000451	50.13	gold quality
granulocyte	CL:0000094	49.19	silver quality
kidney	UBERON:0002113	48.87	gold quality
pancreas	UBERON:0001264	48.62	gold quality
superior frontal gyrus	UBERON:0002661	48.57	silver quality
esophagus mucosa	UBERON:0002469	48.54	gold quality
urinary bladder	UBERON:0001255	48.20	gold quality
mucosa of transverse colon	UBERON:0004991	47.91	gold quality
prostate gland	UBERON:0002367	47.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.