LINC02532

Summary

LINC02532 (long intergenic non-protein coding RNA 2532, HGNC:53549) is a long non-coding RNA gene on chromosome 6q21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53549
Approved symbol	LINC02532
Name	long intergenic non-protein coding RNA 2532
Location	6q21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235142
Ensembl biotype	lncRNA
Entrez	100422737
RNAcentral	URS0000BC44F9 — lncRNA, 1526 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 169 — 167 lncRNA, 2 retained_intron

ENST00000415714, ENST00000418134, ENST00000427903, ENST00000428750, ENST00000430094, ENST00000433965, ENST00000436659, ENST00000602621, ENST00000602934, ENST00000606430, ENST00000607090, ENST00000607758, ENST00000650222, ENST00000653189, ENST00000653256, ENST00000653923, ENST00000654576, ENST00000654718, ENST00000655094, ENST00000655135, ENST00000655499, ENST00000656351, ENST00000657421, ENST00000658326, ENST00000659547, ENST00000659564, ENST00000659907, ENST00000660185, ENST00000660557, ENST00000661417, ENST00000662681, ENST00000663403, ENST00000663790, ENST00000664142, ENST00000664432, ENST00000665697, ENST00000665966, ENST00000667554, ENST00000668203, ENST00000669268, ENST00000669428, ENST00000669890, ENST00000670549, ENST00000670755, ENST00000671150, ENST00000671265, ENST00000671288, ENST00000671512, ENST00000687068, ENST00000687581, ENST00000688514, ENST00000690411, ENST00000690981, ENST00000692919, ENST00000693740, ENST00000700812, ENST00000700821, ENST00000700931, ENST00000700948, ENST00000701118, ENST00000701310, ENST00000701426, ENST00000701462, ENST00000701592, ENST00000701680, ENST00000701739, ENST00000701885, ENST00000701947, ENST00000702011, ENST00000702038, ENST00000702077, ENST00000702196, ENST00000702327, ENST00000702353, ENST00000702360, ENST00000702365, ENST00000844256, ENST00000844257, ENST00000844258, ENST00000844259, ENST00000844260, ENST00000844261, ENST00000844262, ENST00000844263, ENST00000844264, ENST00000844265, ENST00000844266, ENST00000844267, ENST00000844268, ENST00000844269, ENST00000844270, ENST00000844271, ENST00000844272, ENST00000844273, ENST00000844274, ENST00000844275, ENST00000844276, ENST00000844277, ENST00000844278, ENST00000844279, ENST00000844280, ENST00000844281, ENST00000844282, ENST00000844283, ENST00000844284, ENST00000844285, ENST00000844286, ENST00000844287, ENST00000844288, ENST00000844289, ENST00000844290, ENST00000844291, ENST00000844292, ENST00000844293, ENST00000844294, ENST00000844295, ENST00000844296, ENST00000844297, ENST00000844298, ENST00000844299, ENST00000844300, ENST00000844301, ENST00000844302, ENST00000844303, ENST00000844304, ENST00000844305, ENST00000844306, ENST00000844307, ENST00000844308, ENST00000844309, ENST00000844310, ENST00000844311, ENST00000844312, ENST00000844313, ENST00000844314, ENST00000844315, ENST00000844316, ENST00000844317, ENST00000844318, ENST00000844319, ENST00000844320, ENST00000844321, ENST00000844322, ENST00000844323, ENST00000844324, ENST00000844325, ENST00000844326, ENST00000844327, ENST00000844328, ENST00000844329, ENST00000844330, ENST00000844331, ENST00000844332, ENST00000844333, ENST00000844334, ENST00000844335, ENST00000844336, ENST00000844337, ENST00000844338, ENST00000844339, ENST00000844340, ENST00000844341, ENST00000844342, ENST00000844343, ENST00000844344, ENST00000844345, ENST00000844346, ENST00000844347, ENST00000844348

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415714 — 3 exons

Exon	Start	End
ENSE00001790895	106749634	106749788
ENSE00004270945	106787483	106787555
ENSE00004270964	106746346	106747288

Expression profiles

Bgee: expression breadth ubiquitous, 160 present calls, max score 97.65.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.8788 / max 153.9314, expressed in 64 samples.

FANTOM5 promoters (9 alternative TSS)

Promoter ID	TPM avg	Samples expressed
74917	0.3116	27
74912	0.2226	30
74915	0.1410	22
74910	0.0856	27
74913	0.0614	20
74914	0.0229	12
74916	0.0186	11
74909	0.0102	6
74911	0.0049	3

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
metanephros cortex	UBERON:0010533	97.65	gold quality
body of pancreas	UBERON:0001150	97.49	gold quality
right lobe of liver	UBERON:0001114	96.34	gold quality
gall bladder	UBERON:0002110	96.32	gold quality
pancreas	UBERON:0001264	93.05	gold quality
adult mammalian kidney	UBERON:0000082	92.76	gold quality
liver	UBERON:0002107	91.12	gold quality
cortex of kidney	UBERON:0001225	89.62	gold quality
kidney epithelium	UBERON:0004819	89.31	gold quality
kidney	UBERON:0002113	88.78	gold quality
epithelial cell of pancreas	CL:0000083	87.82	gold quality
islet of Langerhans	UBERON:0000006	86.48	gold quality
metanephros	UBERON:0000081	83.10	gold quality
pancreatic ductal cell	CL:0002079	80.58	silver quality
bone marrow cell	CL:0002092	78.99	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.46	gold quality
mucosa of transverse colon	UBERON:0004991	77.99	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.32	gold quality
colonic epithelium	UBERON:0000397	73.22	gold quality
buccal mucosa cell	CL:0002336	72.60	gold quality
cardiac muscle of right atrium	UBERON:0003379	72.20	gold quality
left ventricle myocardium	UBERON:0006566	72.05	gold quality
right uterine tube	UBERON:0001302	71.71	gold quality
body of stomach	UBERON:0001161	70.01	gold quality
upper arm skin	UBERON:0004263	69.19	gold quality
stomach	UBERON:0000945	67.52	gold quality
renal medulla	UBERON:0000362	65.81	gold quality
myocardium	UBERON:0002349	65.23	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.96	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	64.09	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	29.23
E-ANND-3	yes	9.25

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC02532 Contributes to Radiosensitivity in Clear Cell Renal Cell Carcinoma through the miR-654-5p/YY1 Axis. (PMID:34834139)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.