LINC02535

Summary

LINC02535 (long intergenic non-protein coding RNA 2535, HGNC:53569) is a long non-coding RNA gene on chromosome 6q14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53569
Approved symbol	LINC02535
Name	long intergenic non-protein coding RNA 2535
Location	6q14.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234155
Ensembl biotype	lncRNA
Entrez	101928820
RNAcentral	URS0000A76479 — lncRNA, 2529 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000455071, ENST00000840424, ENST00000840425, ENST00000840426, ENST00000840427, ENST00000840428

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000455071 — 2 exons

Exon	Start	End
ENSE00001534969	85387219	85389557
ENSE00004263768	85390013	85390249

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 86.81.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2190 / max 19.3384, expressed in 75 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
74589	0.1010	36
74588	0.0804	25
74590	0.0376	7

Top tissues by expression

183 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ileal mucosa	UBERON:0000331	86.81	gold quality
duodenum	UBERON:0002114	80.51	gold quality
mucosa of transverse colon	UBERON:0004991	78.58	gold quality
jejunal mucosa	UBERON:0000399	77.23	gold quality
pancreatic ductal cell	CL:0002079	77.01	silver quality
rectum	UBERON:0001052	76.51	gold quality
right lobe of liver	UBERON:0001114	76.10	gold quality
buccal mucosa cell	CL:0002336	72.33	silver quality
kidney epithelium	UBERON:0004819	71.12	gold quality
liver	UBERON:0002107	70.14	gold quality
colonic mucosa	UBERON:0000317	68.96	gold quality
metanephros cortex	UBERON:0010533	68.14	gold quality
small intestine	UBERON:0002108	68.07	gold quality
tibialis anterior	UBERON:0001385	67.65	silver quality
gall bladder	UBERON:0002110	67.46	gold quality
mucosa of sigmoid colon	UBERON:0004993	67.31	gold quality
adult mammalian kidney	UBERON:0000082	66.63	gold quality
intestine	UBERON:0000160	66.19	gold quality
gastrocnemius	UBERON:0001388	66.18	silver quality
small intestine Peyer’s patch	UBERON:0003454	65.99	gold quality
colon	UBERON:0001155	65.53	gold quality
large intestine	UBERON:0000059	65.22	gold quality
kidney	UBERON:0002113	64.72	gold quality
transverse colon	UBERON:0001157	64.32	gold quality
jejunum	UBERON:0002115	62.66	gold quality
cortex of kidney	UBERON:0001225	61.73	gold quality
islet of Langerhans	UBERON:0000006	59.10	gold quality
stromal cell of endometrium	CL:0002255	57.75	gold quality
pancreas	UBERON:0001264	57.56	gold quality
deltoid	UBERON:0001476	56.30	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.79

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LINC02535 promotes cell growth in poorly differentiated gastric cancer. (PMID:34125981)
• LncRNA LINC02535 Induces Colorectal Adenocarcinoma Progression via Modulating miR-30d-5p/CHD1. (PMID:36577835)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.