LINC02538

Summary

LINC02538 (long intergenic non-protein coding RNA 2538, HGNC:53571) is a long non-coding RNA gene on chromosome 6q27.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53571
Approved symbol	LINC02538
Name	long intergenic non-protein coding RNA 2538
Location	6q27
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272549
Ensembl biotype	lncRNA
Entrez	401286
RNAcentral	URS000075C7E1 — lncRNA, 4522 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000609107, ENST00000732563, ENST00000732564, ENST00000732565

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000609107 — 3 exons

Exon	Start	End
ENSE00003702648	167678060	167678199
ENSE00003705750	167666840	167670909
ENSE00003709941	167678912	167679270

Expression profiles

Bgee: expression breadth broad, 68 present calls, max score 79.45.

Top tissues by expression

68 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.45	gold quality
lower esophagus mucosa	UBERON:0035834	76.14	gold quality
esophagus mucosa	UBERON:0002469	64.29	gold quality
esophagus	UBERON:0001043	63.96	gold quality
cortical plate	UBERON:0005343	62.48	gold quality
ganglionic eminence	UBERON:0004023	61.31	gold quality
ventricular zone	UBERON:0003053	59.73	gold quality
cortex of kidney	UBERON:0001225	54.02	gold quality
minor salivary gland	UBERON:0001830	53.89	gold quality
left ovary	UBERON:0002119	53.74	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	53.20	gold quality
vagina	UBERON:0000996	53.05	gold quality
saliva-secreting gland	UBERON:0001044	53.05	gold quality
lower esophagus muscularis layer	UBERON:0035833	52.80	gold quality
prefrontal cortex	UBERON:0000451	51.84	silver quality
ectocervix	UBERON:0012249	49.32	gold quality
frontal cortex	UBERON:0001870	48.84	silver quality
ovary	UBERON:0000992	48.72	gold quality
multicellular organism	UBERON:0000468	48.68	gold quality
liver	UBERON:0002107	48.55	silver quality
primary visual cortex	UBERON:0002436	47.40	silver quality
tonsil	UBERON:0002372	46.97	silver quality
heart left ventricle	UBERON:0002084	46.88	silver quality
uterine cervix	UBERON:0000002	46.76	gold quality
placenta	UBERON:0001987	46.38	silver quality
smooth muscle tissue	UBERON:0001135	46.35	silver quality
endometrium	UBERON:0001295	46.32	silver quality
adult mammalian kidney	UBERON:0000082	46.14	silver quality
right lobe of liver	UBERON:0001114	45.80	silver quality
adrenal gland	UBERON:0002369	45.46	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.