LINC02552

Summary

LINC02552 (long intergenic non-protein coding RNA 2552, HGNC:53587) is a long non-coding RNA gene on chromosome 11q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53587
Approved symbol	LINC02552
Name	long intergenic non-protein coding RNA 2552
Location	11q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256422
Ensembl biotype	lncRNA
Entrez	102723895
RNAcentral	URS000075EB14 — lncRNA, 624 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 28 — 28 lncRNA

ENST00000536529, ENST00000538641, ENST00000545630, ENST00000653300, ENST00000653654, ENST00000653969, ENST00000655712, ENST00000658586, ENST00000658606, ENST00000658775, ENST00000659828, ENST00000659889, ENST00000660494, ENST00000661353, ENST00000662458, ENST00000662800, ENST00000664290, ENST00000664724, ENST00000665834, ENST00000666753, ENST00000667686, ENST00000668287, ENST00000669770, ENST00000670375, ENST00000670931, ENST00000702721, ENST00000766697, ENST00000766698

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000536529 — 5 exons

Exon	Start	End
ENSE00002228386	104544699	104544786
ENSE00002230574	104445868	104446012
ENSE00002238878	104512149	104512233
ENSE00002267227	104544876	104545149
ENSE00002284954	104609237	104609296

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 86.07.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2158 / max 55.3521, expressed in 58 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
122064	0.1421	45
122067	0.0533	22
122065	0.0131	6
122066	0.0073	4

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.07	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.32	gold quality
cerebellar cortex	UBERON:0002129	82.49	gold quality
cerebellum	UBERON:0002037	82.42	gold quality
cerebellar hemisphere	UBERON:0002245	82.36	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.97	gold quality
superior frontal gyrus	UBERON:0002661	76.40	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	75.16	gold quality
right frontal lobe	UBERON:0002810	74.20	gold quality
bone marrow cell	CL:0002092	74.18	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.39	gold quality
anterior cingulate cortex	UBERON:0009835	72.90	gold quality
frontal cortex	UBERON:0001870	72.31	gold quality
cerebral cortex	UBERON:0000956	70.99	gold quality
prefrontal cortex	UBERON:0000451	70.54	gold quality
brain	UBERON:0000955	65.87	gold quality
cortical plate	UBERON:0005343	62.15	silver quality
tonsil	UBERON:0002372	62.10	gold quality
substantia nigra	UBERON:0002038	62.08	gold quality
primary visual cortex	UBERON:0002436	61.88	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	59.67	gold quality
sural nerve	UBERON:0015488	59.30	silver quality
Ammon’s horn	UBERON:0001954	59.06	gold quality
bone marrow	UBERON:0002371	59.05	silver quality
stromal cell of endometrium	CL:0002255	58.22	gold quality
ganglionic eminence	UBERON:0004023	57.71	silver quality
amygdala	UBERON:0001876	57.41	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.39	gold quality
ventricular zone	UBERON:0003053	57.13	silver quality
hypothalamus	UBERON:0001898	56.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.