LINC02553

Summary

LINC02553 (long intergenic non-protein coding RNA 2553, HGNC:53588) is a long non-coding RNA gene on chromosome 11q21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53588
Approved symbol	LINC02553
Name	long intergenic non-protein coding RNA 2553
Location	11q21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255039
Ensembl biotype	lncRNA
Entrez	105369449
RNAcentral	URS000000DBDA — lncRNA, 734 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000529088

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000529088 — 3 exons

Exon	Start	End
ENSE00002146738	97222644	97223020
ENSE00002153961	97259446	97259662
ENSE00002163182	97259848	97259987

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 99.73.

Top tissues by expression

36 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	99.73	gold quality
skeletal muscle tissue	UBERON:0001134	75.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.57	gold quality
muscle of leg	UBERON:0001383	67.02	gold quality
gastrocnemius	UBERON:0001388	64.84	gold quality
monocyte	CL:0000576	58.14	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.86	gold quality
blood	UBERON:0000178	51.67	silver quality
prefrontal cortex	UBERON:0000451	51.38	gold quality
esophagus	UBERON:0001043	49.38	gold quality
anterior cingulate cortex	UBERON:0009835	48.81	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	48.66	silver quality
minor salivary gland	UBERON:0001830	48.39	gold quality
heart left ventricle	UBERON:0002084	45.98	gold quality
tibial artery	UBERON:0007610	45.73	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.70	silver quality
ascending aorta	UBERON:0001496	44.23	gold quality
left adrenal gland	UBERON:0001234	44.19	gold quality
primary visual cortex	UBERON:0002436	43.84	silver quality
left adrenal gland cortex	UBERON:0035825	43.74	silver quality
thoracic mammary gland	UBERON:0005200	43.07	silver quality
prostate gland	UBERON:0002367	42.52	gold quality
right atrium auricular region	UBERON:0006631	41.97	silver quality
right adrenal gland cortex	UBERON:0035827	41.74	silver quality
Ammon’s horn	UBERON:0001954	41.59	gold quality
body of pancreas	UBERON:0001150	40.95	silver quality
esophagus mucosa	UBERON:0002469	40.43	silver quality
transverse colon	UBERON:0001157	40.13	silver quality
right frontal lobe	UBERON:0002810	39.88	silver quality
tibial nerve	UBERON:0001323	38.81	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.