LINC02557

Summary

LINC02557 (long intergenic non-protein coding RNA 2557, HGNC:53596) is a long non-coding RNA gene on chromosome 22q11.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53596
Approved symbol	LINC02557
Name	long intergenic non-protein coding RNA 2557
Location	22q11.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225413
Ensembl biotype	lncRNA
Entrez	105372955
RNAcentral	URS000053833C — lncRNA, 477 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000432249

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432249 — 2 exons

Exon	Start	End
ENSE00001647995	23513276	23513602
ENSE00001711085	23512494	23512643

Expression profiles

Bgee: expression breadth broad, 84 present calls, max score 64.71.

Top tissues by expression

84 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
muscle layer of sigmoid colon	UBERON:0035805	64.71	gold quality
colonic epithelium	UBERON:0000397	62.79	silver quality
fundus of stomach	UBERON:0001160	62.60	gold quality
colon	UBERON:0001155	61.53	gold quality
lower esophagus muscularis layer	UBERON:0035833	61.10	gold quality
lower esophagus	UBERON:0013473	61.04	gold quality
intestine	UBERON:0000160	60.86	gold quality
mucosa of stomach	UBERON:0001199	60.34	gold quality
islet of Langerhans	UBERON:0000006	59.29	gold quality
esophagus	UBERON:0001043	58.20	gold quality
prefrontal cortex	UBERON:0000451	58.04	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	57.39	gold quality
small intestine Peyer’s patch	UBERON:0003454	56.66	gold quality
small intestine	UBERON:0002108	56.61	gold quality
duodenum	UBERON:0002114	56.46	gold quality
transverse colon	UBERON:0001157	56.35	gold quality
body of stomach	UBERON:0001161	56.28	gold quality
stomach	UBERON:0000945	56.07	gold quality
frontal cortex	UBERON:0001870	55.68	gold quality
blood	UBERON:0000178	55.62	gold quality
left coronary artery	UBERON:0001626	54.88	gold quality
right ovary	UBERON:0002118	53.53	gold quality
cerebral cortex	UBERON:0000956	52.98	gold quality
gall bladder	UBERON:0002110	52.98	gold quality
right frontal lobe	UBERON:0002810	52.76	gold quality
monocyte	CL:0000576	52.60	silver quality
multicellular organism	UBERON:0000468	52.56	gold quality
vermiform appendix	UBERON:0001154	52.40	gold quality
adenohypophysis	UBERON:0002196	52.04	gold quality
urinary bladder	UBERON:0001255	51.94	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.16

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.