LINC02561

Summary

LINC02561 (long intergenic non-protein coding RNA 2561, HGNC:53601) is a long non-coding RNA gene on chromosome 10p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53601
Approved symbol	LINC02561
Name	long intergenic non-protein coding RNA 2561
Location	10p15.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-445P17.8
Ensembl gene	ENSG00000224034
Ensembl biotype	lncRNA
Entrez	110806285
RNAcentral	URS0000BC45F0 — lncRNA, 736 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000449457

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449457 — 2 exons

Exon	Start	End
ENSE00001667580	5271198	5271236
ENSE00001689003	5265906	5266685

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 70.07.

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	70.07	silver quality
granulocyte	CL:0000094	69.28	gold quality
blood	UBERON:0000178	62.18	gold quality
lymph node	UBERON:0000029	61.39	gold quality
lower esophagus mucosa	UBERON:0035834	59.70	gold quality
right lung	UBERON:0002167	58.62	gold quality
gall bladder	UBERON:0002110	58.51	gold quality
liver	UBERON:0002107	57.68	gold quality
prefrontal cortex	UBERON:0000451	57.41	gold quality
leukocyte	CL:0000738	57.31	gold quality
tonsil	UBERON:0002372	56.57	gold quality
right lobe of liver	UBERON:0001114	56.53	gold quality
metanephros cortex	UBERON:0010533	56.48	gold quality
duodenum	UBERON:0002114	56.33	gold quality
bone marrow	UBERON:0002371	55.94	gold quality
calcaneal tendon	UBERON:0003701	55.87	gold quality
monocyte	CL:0000576	55.52	gold quality
cortex of kidney	UBERON:0001225	55.27	gold quality
islet of Langerhans	UBERON:0000006	55.17	gold quality
upper lobe of left lung	UBERON:0008952	55.09	gold quality
lung	UBERON:0002048	54.47	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.37	gold quality
kidney	UBERON:0002113	53.53	gold quality
stromal cell of endometrium	CL:0002255	53.20	silver quality
urinary bladder	UBERON:0001255	52.14	gold quality
vermiform appendix	UBERON:0001154	51.97	gold quality
adult mammalian kidney	UBERON:0000082	51.49	gold quality
minor salivary gland	UBERON:0001830	51.43	gold quality
saliva-secreting gland	UBERON:0001044	51.42	gold quality
ectocervix	UBERON:0012249	50.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.79

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC02561 promotes metastasis in HCC via HIF1-alpha/NDRG1/UPF1 axis. (PMID:38013127)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.