LINC02568

Summary

LINC02568 (long intergenic non-protein coding RNA 2568, HGNC:51430) is a long non-coding RNA gene on chromosome 15q22.2-q22.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51430
Approved symbol	LINC02568
Name	long intergenic non-protein coding RNA 2568
Location	15q22.2-q22.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259459
Ensembl biotype	lncRNA
Entrez	102723344
RNAcentral	URS000075D1AA — lncRNA, 1204 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000559379, ENST00000559821, ENST00000662408, ENST00000821131

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000559379 — 6 exons

Exon	Start	End
ENSE00002538302	63394851	63394911
ENSE00002540116	63431057	63431342
ENSE00002544077	63395601	63395681
ENSE00002546046	63432152	63432177
ENSE00002567853	63398387	63398467
ENSE00002571305	63390136	63390261

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 81.68.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0470 / max 11.7166, expressed in 18 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
147123	0.0470	18

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.68	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	81.29	gold quality
mucosa of transverse colon	UBERON:0004991	80.26	gold quality
body of pancreas	UBERON:0001150	78.05	gold quality
saliva-secreting gland	UBERON:0001044	77.00	gold quality
minor salivary gland	UBERON:0001830	76.60	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.86	silver quality
tonsil	UBERON:0002372	71.45	gold quality
pancreas	UBERON:0001264	71.30	gold quality
transverse colon	UBERON:0001157	70.80	gold quality
rectum	UBERON:0001052	70.06	gold quality
gall bladder	UBERON:0002110	66.44	gold quality
colonic epithelium	UBERON:0000397	65.32	silver quality
skin of leg	UBERON:0001511	65.01	gold quality
adult mammalian kidney	UBERON:0000082	64.71	gold quality
colon	UBERON:0001155	64.18	gold quality
ganglionic eminence	UBERON:0004023	63.82	gold quality
kidney	UBERON:0002113	63.77	gold quality
zone of skin	UBERON:0000014	63.64	gold quality
metanephros cortex	UBERON:0010533	63.00	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.68	gold quality
cortex of kidney	UBERON:0001225	62.20	gold quality
thoracic mammary gland	UBERON:0005200	61.99	gold quality
ventricular zone	UBERON:0003053	61.88	gold quality
skin of abdomen	UBERON:0001416	61.85	gold quality
thyroid gland	UBERON:0002046	61.30	gold quality
cortical plate	UBERON:0005343	61.25	gold quality
intestine	UBERON:0000160	60.06	gold quality
skeletal muscle tissue	UBERON:0001134	59.82	silver quality
left lobe of thyroid gland	UBERON:0001120	59.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.39

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long noncoding RNA LINC02568 sequesters microRNA-874-3p to facilitate malignancy in breast cancer cells via cyclin E1 overexpression. (PMID:37303942)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.