LINC02570

Summary

LINC02570 (long intergenic non-protein coding RNA 2570, HGNC:39766) is a long non-coding RNA gene on chromosome 6p21.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:39766
Approved symbol	LINC02570
Name	long intergenic non-protein coding RNA 2570
Location	6p21.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	XXbac-BPG27H4.8
Ensembl gene	ENSG00000237923
Ensembl biotype	lncRNA
Entrez	105375014
RNAcentral	URS0000A7648E — lncRNA, 796 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000442852, ENST00000702471, ENST00000810494, ENST00000810495, ENST00000810496, ENST00000810497, ENST00000810498

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000442852 — 3 exons

Exon	Start	End
ENSE00001660885	30847037	30847149
ENSE00004207419	30847968	30848256
ENSE00004207428	30839075	30840019

Expression profiles

Bgee: expression breadth broad, 70 present calls, max score 82.49.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1599 / max 18.9207, expressed in 42 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
72618	0.1599	42

Top tissues by expression

70 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.49	gold quality
ventricular zone	UBERON:0003053	62.95	gold quality
left ovary	UBERON:0002119	59.34	gold quality
urinary bladder	UBERON:0001255	58.87	gold quality
ectocervix	UBERON:0012249	57.30	gold quality
myometrium	UBERON:0001296	55.23	gold quality
endometrium	UBERON:0001295	54.86	gold quality
lymph node	UBERON:0000029	52.95	gold quality
ovary	UBERON:0000992	52.85	gold quality
primary visual cortex	UBERON:0002436	51.78	gold quality
blood	UBERON:0000178	51.19	silver quality
placenta	UBERON:0001987	50.85	gold quality
monocyte	CL:0000576	50.79	silver quality
skin of abdomen	UBERON:0001416	50.24	gold quality
zone of skin	UBERON:0000014	50.13	gold quality
skin of leg	UBERON:0001511	49.92	gold quality
cortex of kidney	UBERON:0001225	49.69	silver quality
right lung	UBERON:0002167	49.57	gold quality
minor salivary gland	UBERON:0001830	49.10	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	48.55	gold quality
vagina	UBERON:0000996	48.38	gold quality
fallopian tube	UBERON:0003889	47.86	gold quality
lung	UBERON:0002048	47.40	gold quality
upper lobe of left lung	UBERON:0008952	45.82	gold quality
multicellular organism	UBERON:0000468	45.62	gold quality
Ammon’s horn	UBERON:0001954	45.57	gold quality
esophagus	UBERON:0001043	45.43	gold quality
esophagus mucosa	UBERON:0002469	45.30	gold quality
heart left ventricle	UBERON:0002084	45.25	silver quality
muscle of leg	UBERON:0001383	45.22	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long intergenic non-protein coding RNA 02570 promotes nasopharyngeal carcinoma progression by adsorbing microRNA miR-4649-3p thereby upregulating both sterol regulatory element binding protein 1, and fatty acid synthase. (PMID:34546840)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.