LINC02574

Summary

LINC02574 (long intergenic non-protein coding RNA 2574, HGNC:53746) is a long non-coding RNA gene on chromosome 1p35.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53746
Approved symbol	LINC02574
Name	long intergenic non-protein coding RNA 2574
Location	1p35.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-288L9.1, HEAL
Ensembl gene	ENSG00000233975
Ensembl biotype	lncRNA
Entrez	111216282
RNAcentral	URS00001E0AA0 — lncRNA, 441 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000440492, ENST00000681370

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440492 — 2 exons

Exon	Start	End
ENSE00004048949	27660327	27660722
ENSE00004048950	27662677	27663333

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 90.50.

FANTOM5 (CAGE): breadth broad, TPM avg 1.0900 / max 315.5619, expressed in 360 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
11291	0.4559	198
11288	0.2176	70
11290	0.1648	59
11292	0.1026	46
11289	0.0799	22
11287	0.0691	23

Top tissues by expression

224 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.50	silver quality
pancreatic ductal cell	CL:0002079	74.97	silver quality
tibialis anterior	UBERON:0001385	74.34	gold quality
kidney epithelium	UBERON:0004819	74.03	gold quality
left ventricle myocardium	UBERON:0006566	69.02	gold quality
cardiac muscle of right atrium	UBERON:0003379	68.99	gold quality
upper arm skin	UBERON:0004263	66.37	gold quality
myocardium	UBERON:0002349	66.24	gold quality
nasal cavity epithelium	UBERON:0005384	65.30	gold quality
deltoid	UBERON:0001476	64.40	silver quality
bone marrow cell	CL:0002092	63.18	silver quality
monocyte	CL:0000576	63.00	gold quality
quadriceps femoris	UBERON:0001377	62.65	gold quality
vena cava	UBERON:0004087	60.92	gold quality
vastus lateralis	UBERON:0001379	60.91	gold quality
ileal mucosa	UBERON:0000331	60.89	gold quality
heart right ventricle	UBERON:0002080	60.73	gold quality
biceps brachii	UBERON:0001507	60.29	gold quality
descending thoracic aorta	UBERON:0002345	60.16	gold quality
calcaneal tendon	UBERON:0003701	58.82	gold quality
gall bladder	UBERON:0002110	58.64	gold quality
prefrontal cortex	UBERON:0000451	58.10	gold quality
islet of Langerhans	UBERON:0000006	57.80	gold quality
secondary oocyte	CL:0000655	57.42	gold quality
bone marrow	UBERON:0002371	57.32	gold quality
vermiform appendix	UBERON:0001154	56.72	gold quality
lateral nuclear group of thalamus	UBERON:0002736	56.45	gold quality
parotid gland	UBERON:0001831	56.18	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	55.80	gold quality
upper leg skin	UBERON:0004262	55.59	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.