LINC02575

Summary

LINC02575 (long intergenic non-protein coding RNA 2575, HGNC:53747) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53747
Approved symbol	LINC02575
Name	long intergenic non-protein coding RNA 2575
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AP001065.15
Ensembl gene	ENSG00000228709
Ensembl biotype	lncRNA
Entrez	111216286
RNAcentral	URS0000D78084 — lncRNA, 1409 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000449713, ENST00000622854, ENST00000698336

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449713 — 2 exons

Exon	Start	End
ENSE00001681181	44490031	44491142
ENSE00001752545	44485486	44486230

Expression profiles

Bgee: expression breadth ubiquitous, 141 present calls, max score 85.73.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.6183 / max 98.0080, expressed in 156 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
189488	0.6183	156

Top tissues by expression

232 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.73	gold quality
right lobe of liver	UBERON:0001114	82.21	gold quality
secondary oocyte	CL:0000655	81.51	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.74	gold quality
buccal mucosa cell	CL:0002336	75.12	silver quality
sperm	CL:0000019	72.34	gold quality
liver	UBERON:0002107	71.56	gold quality
cortical plate	UBERON:0005343	68.34	gold quality
nasal cavity epithelium	UBERON:0005384	66.55	gold quality
esophagus squamous epithelium	UBERON:0006920	65.86	gold quality
parotid gland	UBERON:0001831	65.66	gold quality
heart right ventricle	UBERON:0002080	65.55	gold quality
oocyte	CL:0000023	65.27	gold quality
ganglionic eminence	UBERON:0004023	65.10	gold quality
ventricular zone	UBERON:0003053	64.45	gold quality
mucosa of stomach	UBERON:0001199	63.56	gold quality
oral cavity	UBERON:0000167	62.36	gold quality
gingiva	UBERON:0001828	62.12	gold quality
left testis	UBERON:0004533	61.95	gold quality
testis	UBERON:0000473	61.58	gold quality
muscle layer of sigmoid colon	UBERON:0035805	61.10	gold quality
bronchial epithelial cell	CL:0002328	59.39	gold quality
bronchus	UBERON:0002185	59.23	gold quality
right testis	UBERON:0004534	58.92	gold quality
granulocyte	CL:0000094	58.74	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	58.58	gold quality
gingival epithelium	UBERON:0001949	58.57	gold quality
body of uterus	UBERON:0009853	58.54	gold quality
left uterine tube	UBERON:0001303	58.35	gold quality
myometrium	UBERON:0001296	57.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.