LINC02577

Summary

LINC02577 (long intergenic non-protein coding RNA 2577, HGNC:53749) is a long non-coding RNA gene on chromosome 7q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53749
Approved symbol	LINC02577
Name	long intergenic non-protein coding RNA 2577
Location	7q22.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC002384.1, SLINKY, CLAN
Ensembl gene	ENSG00000228742
Ensembl biotype	lncRNA
Entrez	111216280
RNAcentral	URS000212316C — lncRNA, 613 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000470135, ENST00000490162, ENST00000602761, ENST00000636036, ENST00000650196, ENST00000655590, ENST00000658697, ENST00000659396, ENST00000659665, ENST00000789448, ENST00000789449, ENST00000789450, ENST00000789451, ENST00000789452, ENST00000789453

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000470135 — 4 exons

Exon	Start	End
ENSE00001809982	106775076	106775200
ENSE00001823716	106777542	106777732
ENSE00001831203	106780650	106780942
ENSE00001950886	106775959	106776022

Expression profiles

Bgee: expression breadth ubiquitous, 148 present calls, max score 78.65.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7584 / max 63.6453, expressed in 210 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
80405	0.6397	200
204642	0.0892	57
80404	0.0296	14

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.65	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.92	gold quality
buccal mucosa cell	CL:0002336	70.26	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.96	gold quality
ventricular zone	UBERON:0003053	65.38	gold quality
bone marrow cell	CL:0002092	62.43	silver quality
monocyte	CL:0000576	61.92	gold quality
right testis	UBERON:0004534	61.21	gold quality
ganglionic eminence	UBERON:0004023	61.14	gold quality
left testis	UBERON:0004533	60.48	gold quality
testis	UBERON:0000473	59.34	gold quality
stromal cell of endometrium	CL:0002255	58.04	gold quality
upper leg skin	UBERON:0004262	57.12	silver quality
right adrenal gland cortex	UBERON:0035827	55.33	gold quality
sural nerve	UBERON:0015488	55.00	silver quality
nasal cavity mucosa	UBERON:0001826	54.77	gold quality
mucosa of transverse colon	UBERON:0004991	54.47	gold quality
islet of Langerhans	UBERON:0000006	52.77	gold quality
prefrontal cortex	UBERON:0000451	52.76	gold quality
right coronary artery	UBERON:0001625	52.33	gold quality
blood	UBERON:0000178	52.18	gold quality
right adrenal gland	UBERON:0001233	51.57	gold quality
granulocyte	CL:0000094	51.25	silver quality
muscle of leg	UBERON:0001383	50.87	gold quality
upper lobe of left lung	UBERON:0008952	50.51	gold quality
left adrenal gland	UBERON:0001234	50.46	gold quality
smooth muscle tissue	UBERON:0001135	50.25	gold quality
adrenal gland	UBERON:0002369	50.17	gold quality
adrenal cortex	UBERON:0001235	50.01	gold quality
gall bladder	UBERON:0002110	49.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.