LINC02582

Summary

LINC02582 (long intergenic non-protein coding RNA 2582, HGNC:53792) is a long non-coding RNA gene on chromosome 18q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53792
Approved symbol	LINC02582
Name	long intergenic non-protein coding RNA 2582
Location	18q22.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	CTD-2354A18.1
Ensembl gene	ENSG00000261780
Ensembl biotype	lncRNA
Entrez	100505817
RNAcentral	URS000075B4BA — lncRNA, 1181 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 31 — 30 lncRNA, 1 retained_intron

ENST00000563172, ENST00000577634, ENST00000583942, ENST00000653686, ENST00000659659, ENST00000660490, ENST00000664821, ENST00000666831, ENST00000786158, ENST00000786159, ENST00000786160, ENST00000786161, ENST00000786162, ENST00000786163, ENST00000786164, ENST00000786165, ENST00000786166, ENST00000786167, ENST00000786168, ENST00000786169, ENST00000786170, ENST00000786171, ENST00000786172, ENST00000786173, ENST00000786174, ENST00000786175, ENST00000786176, ENST00000786177, ENST00000786178, ENST00000786179, ENST00000786180

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563172 — 3 exons

Exon	Start	End
ENSE00002222011	73324941	73325193
ENSE00002577733	73332465	73332581
ENSE00002705729	73349084	73349879

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 85.34.

Top tissues by expression

193 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.34	gold quality
buccal mucosa cell	CL:0002336	80.90	gold quality
bone marrow cell	CL:0002092	74.68	silver quality
colonic epithelium	UBERON:0000397	73.00	gold quality
sural nerve	UBERON:0015488	69.11	silver quality
cortical plate	UBERON:0005343	59.08	silver quality
uterine cervix	UBERON:0000002	55.77	silver quality
monocyte	CL:0000576	55.71	gold quality
stromal cell of endometrium	CL:0002255	54.62	silver quality
tonsil	UBERON:0002372	53.55	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.08	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	50.30	gold quality
pancreas	UBERON:0001264	49.99	gold quality
body of pancreas	UBERON:0001150	49.37	gold quality
urinary bladder	UBERON:0001255	49.26	silver quality
skeletal muscle tissue	UBERON:0001134	48.92	gold quality
calcaneal tendon	UBERON:0003701	48.90	silver quality
muscle of leg	UBERON:0001383	47.73	gold quality
prefrontal cortex	UBERON:0000451	46.61	silver quality
gastrocnemius	UBERON:0001388	46.59	gold quality
adult mammalian kidney	UBERON:0000082	46.19	silver quality
kidney	UBERON:0002113	46.11	silver quality
islet of Langerhans	UBERON:0000006	46.09	gold quality
skin of leg	UBERON:0001511	46.05	gold quality
cortex of kidney	UBERON:0001225	46.03	gold quality
vermiform appendix	UBERON:0001154	45.98	silver quality
adrenal gland	UBERON:0002369	45.43	silver quality
blood	UBERON:0000178	45.21	silver quality
heart left ventricle	UBERON:0002084	45.09	gold quality
small intestine	UBERON:0002108	44.79	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.94

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long noncoding RNA LINC02582 acts downstream of miR-200c to promote radioresistance through CHK1 in breast cancer cells. (PMID:31601781)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.