LINC02583

Summary

LINC02583 (long intergenic non-protein coding RNA 2583, HGNC:53812) is a long non-coding RNA gene on chromosome 2p21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53812
Approved symbol	LINC02583
Name	long intergenic non-protein coding RNA 2583
Location	2p21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000187600
Ensembl biotype	lncRNA
Entrez	101805491
RNAcentral	URS000075AA12 — lncRNA, 756 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 42 — 42 lncRNA

ENST00000415396, ENST00000416466, ENST00000449601, ENST00000642724, ENST00000843637, ENST00000843638, ENST00000843639, ENST00000843640, ENST00000843641, ENST00000843642, ENST00000843643, ENST00000843644, ENST00000843645, ENST00000843646, ENST00000843647, ENST00000843648, ENST00000843649, ENST00000843650, ENST00000843651, ENST00000843652, ENST00000843653, ENST00000843654, ENST00000843655, ENST00000843656, ENST00000843657, ENST00000843658, ENST00000843659, ENST00000843660, ENST00000843661, ENST00000843662, ENST00000843663, ENST00000843664, ENST00000843665, ENST00000843666, ENST00000843667, ENST00000843668, ENST00000843669, ENST00000843670, ENST00000843671, ENST00000843672, ENST00000843673, ENST00000843674

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415396 — 4 exons

Exon	Start	End
ENSE00001725929	46436473	46436696
ENSE00001770794	46441559	46441832
ENSE00001785735	46441292	46441371
ENSE00003812182	46440127	46440226

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 93.36.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4286 / max 84.9098, expressed in 67 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
20088	0.1646	55
20086	0.1414	47
20087	0.1227	48

Top tissues by expression

181 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.36	gold quality
colonic epithelium	UBERON:0000397	74.60	gold quality
sperm	CL:0000019	74.31	gold quality
placenta	UBERON:0001987	68.47	gold quality
right testis	UBERON:0004534	66.14	gold quality
left testis	UBERON:0004533	65.91	gold quality
testis	UBERON:0000473	65.35	gold quality
buccal mucosa cell	CL:0002336	64.99	silver quality
cortical plate	UBERON:0005343	64.27	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.11	gold quality
sural nerve	UBERON:0015488	60.46	silver quality
calcaneal tendon	UBERON:0003701	60.06	gold quality
monocyte	CL:0000576	56.78	gold quality
myocardium	UBERON:0002349	53.00	gold quality
parotid gland	UBERON:0001831	52.50	gold quality
adult organism	UBERON:0007023	51.27	gold quality
left uterine tube	UBERON:0001303	50.95	gold quality
islet of Langerhans	UBERON:0000006	50.81	gold quality
skeletal muscle tissue	UBERON:0001134	50.34	gold quality
saliva-secreting gland	UBERON:0001044	49.95	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.52	gold quality
blood	UBERON:0000178	49.08	gold quality
gastrocnemius	UBERON:0001388	48.90	gold quality
deltoid	UBERON:0001476	48.44	gold quality
prefrontal cortex	UBERON:0000451	47.82	gold quality
thyroid gland	UBERON:0002046	47.26	silver quality
bone marrow	UBERON:0002371	46.74	gold quality
vastus lateralis	UBERON:0001379	46.47	gold quality
quadriceps femoris	UBERON:0001377	46.32	gold quality
Brodmann (1909) area 9	UBERON:0013540	46.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.