LINC02584

Summary

LINC02584 (long intergenic non-protein coding RNA 2584, HGNC:33275) is a long non-coding RNA gene on chromosome 11q13.3.

Predicted to enable U4 snRNA binding activity. Predicted to be involved in formation of quadruple SL/U4/U5/U6 snRNP and spliceosomal tri-snRNP complex assembly. Predicted to be part of U4/U6 x U5 tri-snRNP complex and U6 snRNP.

Source: NCBI Gene 100009613 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33275
Approved symbol	LINC02584
Name	long intergenic non-protein coding RNA 2584
Location	11q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254417
Ensembl biotype	lncRNA
Entrez	100009613
RNAcentral	URS000075BC24 — lncRNA, 804 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000531347, ENST00000533327, ENST00000777707, ENST00000777708, ENST00000777710, ENST00000777712, ENST00000777713, ENST00000777714, ENST00000777715, ENST00000777716

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000531347 — 2 exons

Exon	Start	End
ENSE00002170646	70074936	70075433
ENSE00002197798	70072434	70072939

Expression profiles

Bgee: expression breadth broad, 81 present calls, max score 88.26.

Top tissues by expression

81 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.26	silver quality
left testis	UBERON:0004533	73.58	gold quality
testis	UBERON:0000473	73.20	gold quality
right testis	UBERON:0004534	73.18	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.90	gold quality
liver	UBERON:0002107	58.95	gold quality
monocyte	CL:0000576	55.38	gold quality
right lobe of liver	UBERON:0001114	53.55	gold quality
blood	UBERON:0000178	53.30	gold quality
amygdala	UBERON:0001876	51.35	gold quality
ascending aorta	UBERON:0001496	50.86	gold quality
prefrontal cortex	UBERON:0000451	50.64	gold quality
thoracic aorta	UBERON:0001515	50.54	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.50	gold quality
islet of Langerhans	UBERON:0000006	50.09	gold quality
thoracic mammary gland	UBERON:0005200	49.85	gold quality
multicellular organism	UBERON:0000468	49.67	gold quality
gastrocnemius	UBERON:0001388	48.61	gold quality
muscle of leg	UBERON:0001383	48.50	gold quality
gall bladder	UBERON:0002110	47.49	gold quality
descending thoracic aorta	UBERON:0002345	46.71	gold quality
vermiform appendix	UBERON:0001154	46.63	silver quality
right atrium auricular region	UBERON:0006631	46.05	gold quality
skin of leg	UBERON:0001511	45.76	gold quality
calcaneal tendon	UBERON:0003701	45.59	silver quality
heart	UBERON:0000948	45.54	gold quality
tibial artery	UBERON:0007610	45.42	gold quality
heart left ventricle	UBERON:0002084	45.31	silver quality
zone of skin	UBERON:0000014	45.17	gold quality
fallopian tube	UBERON:0003889	44.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.31

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Investigating the regulatory function of the ANO1-AS2 on the ANO1 gene in infertile men with asthenozoospermia and terato-asthenozoospermia. (PMID:32916161)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.