LINC02591

Summary

LINC02591 (long intergenic non-protein coding RNA 2591, HGNC:53901) is a long non-coding RNA gene on chromosome 1q21.1.

Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translation.

Source: NCBI Gene 388692 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53901
Approved symbol	LINC02591
Name	long intergenic non-protein coding RNA 2591
Location	1q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000263590
Ensembl biotype	lncRNA
Entrez	388692
RNAcentral	URS000075A711 — lncRNA, 2307 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000424684, ENST00000824696

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424684 — 2 exons

Exon	Start	End
ENSE00001610237	143790010	143790263
ENSE00003720347	143792120	143797108

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 58.26.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	58.26	gold quality
blood	UBERON:0000178	55.70	gold quality
lymph node	UBERON:0000029	52.44	gold quality
leukocyte	CL:0000738	51.77	silver quality
prefrontal cortex	UBERON:0000451	51.71	gold quality
monocyte	CL:0000576	50.22	silver quality
liver	UBERON:0002107	49.85	silver quality
vermiform appendix	UBERON:0001154	49.30	gold quality
islet of Langerhans	UBERON:0000006	47.53	gold quality
bone marrow	UBERON:0002371	47.51	silver quality
right lobe of liver	UBERON:0001114	47.29	silver quality
right lobe of thyroid gland	UBERON:0001119	47.28	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	47.01	gold quality
cortex of kidney	UBERON:0001225	46.66	silver quality
placenta	UBERON:0001987	46.48	gold quality
gall bladder	UBERON:0002110	46.28	silver quality
muscle layer of sigmoid colon	UBERON:0035805	46.18	gold quality
frontal cortex	UBERON:0001870	46.08	gold quality
spleen	UBERON:0002106	45.87	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	45.78	silver quality
superior frontal gyrus	UBERON:0002661	45.64	silver quality
lower esophagus	UBERON:0013473	45.64	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.61	gold quality
endometrium	UBERON:0001295	45.54	silver quality
tonsil	UBERON:0002372	45.50	silver quality
urinary bladder	UBERON:0001255	45.48	gold quality
pancreas	UBERON:0001264	45.32	silver quality
muscle tissue	UBERON:0002385	45.31	silver quality
primary visual cortex	UBERON:0002436	45.16	silver quality
thyroid gland	UBERON:0002046	45.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.99

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.