LINC02594

Summary

LINC02594 (long intergenic non-protein coding RNA 2594, HGNC:53935) is a long non-coding RNA gene on chromosome 17q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53935
Approved symbol	LINC02594
Name	long intergenic non-protein coding RNA 2594
Location	17q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267440
Ensembl biotype	lncRNA
Entrez	105371786
RNAcentral	URS00026A20E4 — lncRNA, 1618 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000593169

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000593169 — 3 exons

Exon	Start	End
ENSE00002865198	43705429	43706709
ENSE00002959067	43680266	43680365
ENSE00003885370	43679341	43679435

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 62.88.

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	62.88	silver quality
cortical plate	UBERON:0005343	61.73	silver quality
ganglionic eminence	UBERON:0004023	57.94	silver quality
right adrenal gland cortex	UBERON:0035827	57.07	gold quality
lymph node	UBERON:0000029	57.05	gold quality
left adrenal gland	UBERON:0001234	55.09	gold quality
adrenal gland	UBERON:0002369	55.06	gold quality
stromal cell of endometrium	CL:0002255	54.34	silver quality
right adrenal gland	UBERON:0001233	53.80	gold quality
left adrenal gland cortex	UBERON:0035825	53.46	gold quality
skeletal muscle tissue	UBERON:0001134	52.68	silver quality
fallopian tube	UBERON:0003889	52.09	gold quality
spleen	UBERON:0002106	51.48	gold quality
right uterine tube	UBERON:0001302	51.38	gold quality
ectocervix	UBERON:0012249	51.31	gold quality
blood	UBERON:0000178	51.24	silver quality
placenta	UBERON:0001987	50.46	gold quality
monocyte	CL:0000576	50.39	silver quality
nucleus accumbens	UBERON:0001882	50.33	gold quality
prefrontal cortex	UBERON:0000451	50.26	gold quality
skin of leg	UBERON:0001511	50.09	gold quality
bone marrow	UBERON:0002371	50.05	silver quality
subcutaneous adipose tissue	UBERON:0002190	49.76	gold quality
frontal cortex	UBERON:0001870	49.48	gold quality
zone of skin	UBERON:0000014	49.36	gold quality
calcaneal tendon	UBERON:0003701	49.36	silver quality
superior frontal gyrus	UBERON:0002661	49.25	silver quality
tibial nerve	UBERON:0001323	49.06	gold quality
right frontal lobe	UBERON:0002810	48.98	gold quality
mucosa of stomach	UBERON:0001199	48.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LncRNAs CTC-501O10.1, AC100830.4 and RP11-210K20.5 were up-regulated in the plasma of gastric cancer patients. (PMID:29700972)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.