LINC02603

Summary

LINC02603 (long intergenic non-protein coding RNA 2603, HGNC:37186) is a long non-coding RNA gene on chromosome 9q22.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37186
Approved symbol	LINC02603
Name	long intergenic non-protein coding RNA 2603
Location	9q22.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230262
Ensembl biotype	lncRNA
Entrez	158257
RNAcentral	URS000075ED32 — lncRNA, 1362 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000416309, ENST00000602602, ENST00000602652, ENST00000651632, ENST00000654029, ENST00000666068, ENST00000668497, ENST00000710613, ENST00000803259

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416309 — 4 exons

Exon	Start	End
ENSE00001602676	94199198	94199251
ENSE00001650372	94200814	94200872
ENSE00004012567	94176602	94177731
ENSE00004012568	94204493	94204543

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 96.72.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4627 / max 71.7739, expressed in 137 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
101506	0.4627	137

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
oviduct epithelium	UBERON:0004804	96.72	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.29	gold quality
buccal mucosa cell	CL:0002336	80.13	gold quality
colonic epithelium	UBERON:0000397	78.36	gold quality
sperm	CL:0000019	77.64	gold quality
sural nerve	UBERON:0015488	75.86	gold quality
adrenal tissue	UBERON:0018303	73.42	gold quality
calcaneal tendon	UBERON:0003701	72.45	gold quality
bone marrow cell	CL:0002092	69.71	silver quality
tendon	UBERON:0000043	67.79	gold quality
fallopian tube	UBERON:0003889	67.02	gold quality
stromal cell of endometrium	CL:0002255	65.16	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.17	gold quality
corpus callosum	UBERON:0002336	62.38	gold quality
cortical plate	UBERON:0005343	61.48	gold quality
tonsil	UBERON:0002372	60.12	gold quality
tendon of biceps brachii	UBERON:0008188	59.52	silver quality
monocyte	CL:0000576	59.23	gold quality
right lobe of thyroid gland	UBERON:0001119	59.12	gold quality
apex of heart	UBERON:0002098	59.02	gold quality
leukocyte	CL:0000738	58.90	gold quality
right adrenal gland	UBERON:0001233	58.61	gold quality
body of pancreas	UBERON:0001150	58.44	gold quality
adrenal gland	UBERON:0002369	57.65	gold quality
lower esophagus mucosa	UBERON:0035834	57.43	gold quality
blood	UBERON:0000178	57.27	gold quality
right adrenal gland cortex	UBERON:0035827	56.84	gold quality
pancreas	UBERON:0001264	56.77	gold quality
lower esophagus	UBERON:0013473	56.51	gold quality
lower esophagus muscularis layer	UBERON:0035833	56.49	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.07

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• miR-25-3p and let-7d-5p in plasma were differentially expressed between Acute exacerbation of idiopathic pulmonary fibrosis and stable idiopathic pulmonary fibrosis (PMID:27881157)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.