LINC02605

Summary

LINC02605 (long intergenic non-protein coding RNA 2605, HGNC:53974) is a long non-coding RNA gene on chromosome 8q21.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53974
Approved symbol	LINC02605
Name	long intergenic non-protein coding RNA 2605
Location	8q21.13
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-79H23.3, IL-7-AS, AC083837.1
Ensembl gene	ENSG00000261618
Ensembl biotype	lncRNA
Entrez	112935892
RNAcentral	URS00004656A3 — lncRNA, 2994 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000565297

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000565297 — 1 exons

Exon	Start	End
ENSE00002583800	78835307	78840525

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 65.57.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	65.57	gold quality
colonic epithelium	UBERON:0000397	63.19	silver quality
tonsil	UBERON:0002372	61.02	gold quality
corpus callosum	UBERON:0002336	60.99	gold quality
substantia nigra	UBERON:0002038	60.69	gold quality
liver	UBERON:0002107	59.93	gold quality
myometrium	UBERON:0001296	59.83	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.13	gold quality
calcaneal tendon	UBERON:0003701	57.16	gold quality
bone marrow	UBERON:0002371	56.34	gold quality
amygdala	UBERON:0001876	55.28	gold quality
vermiform appendix	UBERON:0001154	55.17	gold quality
right lobe of liver	UBERON:0001114	54.22	gold quality
islet of Langerhans	UBERON:0000006	53.94	gold quality
lymph node	UBERON:0000029	52.45	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	52.43	gold quality
duodenum	UBERON:0002114	52.26	gold quality
gall bladder	UBERON:0002110	52.18	gold quality
upper lobe of left lung	UBERON:0008952	51.38	gold quality
lung	UBERON:0002048	51.30	gold quality
omental fat pad	UBERON:0010414	51.13	gold quality
fallopian tube	UBERON:0003889	50.69	gold quality
skin of abdomen	UBERON:0001416	50.51	gold quality
adrenal tissue	UBERON:0018303	50.48	silver quality
monocyte	CL:0000576	50.30	silver quality
body of pancreas	UBERON:0001150	49.91	gold quality
endometrium	UBERON:0001295	49.78	silver quality
urinary bladder	UBERON:0001255	49.73	gold quality
right frontal lobe	UBERON:0002810	49.46	gold quality
blood	UBERON:0000178	49.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.63

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• first demonstrated that RP11-79H23.3 might suppress the pathogenesis and development of BC by acting as a sponge for miR-107 to increase PTEN expression. (PMID:30149689)
• Interferon-Inducible LINC02605 Promotes Antiviral Innate Responses by Strengthening IRF3 Nuclear Translocation. (PMID:34804040)
• LINC02605 involved in paediatric Mycoplasma pneumoniae pneumonia complicated with diarrhoea via miR-539-5p/CXCL1 axis. (PMID:38662581)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.