LINC02643

Summary

LINC02643 (long intergenic non-protein coding RNA 2643, HGNC:54126) is a long non-coding RNA gene on chromosome 10p12.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54126
Approved symbol	LINC02643
Name	long intergenic non-protein coding RNA 2643
Location	10p12.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230109
Ensembl biotype	lncRNA
Entrez	105376444
RNAcentral	URS0000529FE3 — lncRNA, 439 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000433460, ENST00000737361, ENST00000737362, ENST00000737363, ENST00000737364

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433460 — 5 exons

Exon	Start	End
ENSE00001607392	21368497	21368555
ENSE00001681335	21372895	21372950
ENSE00001735144	21340233	21340313
ENSE00001794797	21369967	21370115
ENSE00001797478	21354671	21354764

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 59.92.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1948 / max 37.4846, expressed in 36 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
108610	0.1948	36

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
muscle tissue	UBERON:0002385	59.92	silver quality
endometrium	UBERON:0001295	59.58	gold quality
bone marrow	UBERON:0002371	58.40	gold quality
adrenal tissue	UBERON:0018303	57.30	gold quality
blood	UBERON:0000178	56.82	gold quality
lymph node	UBERON:0000029	56.71	gold quality
corpus callosum	UBERON:0002336	56.67	gold quality
monocyte	CL:0000576	55.19	gold quality
cortex of kidney	UBERON:0001225	53.91	gold quality
ovary	UBERON:0000992	50.87	gold quality
placenta	UBERON:0001987	50.20	gold quality
left ovary	UBERON:0002119	49.98	gold quality
muscle of leg	UBERON:0001383	49.72	gold quality
stomach	UBERON:0000945	49.34	gold quality
gastrocnemius	UBERON:0001388	49.04	gold quality
right ovary	UBERON:0002118	48.82	gold quality
kidney	UBERON:0002113	48.15	gold quality
prefrontal cortex	UBERON:0000451	48.00	silver quality
tibial artery	UBERON:0007610	46.55	gold quality
fallopian tube	UBERON:0003889	46.54	gold quality
lung	UBERON:0002048	46.22	gold quality
heart left ventricle	UBERON:0002084	45.45	silver quality
body of pancreas	UBERON:0001150	45.38	silver quality
multicellular organism	UBERON:0000468	45.13	gold quality
adrenal gland	UBERON:0002369	44.69	gold quality
myometrium	UBERON:0001296	44.60	gold quality
ascending aorta	UBERON:0001496	44.60	gold quality
heart	UBERON:0000948	44.16	gold quality
thoracic aorta	UBERON:0001515	44.03	gold quality
Brodmann (1909) area 9	UBERON:0013540	43.97	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.