LINC02646

Summary

LINC02646 (long intergenic non-protein coding RNA 2646, HGNC:54130) is a long non-coding RNA gene on chromosome 10q26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54130
Approved symbol	LINC02646
Name	long intergenic non-protein coding RNA 2646
Location	10q26.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236303
Ensembl biotype	lncRNA
Entrez	107984002
RNAcentral	URS0002A64CA5 — lncRNA, 1587 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000439421, ENST00000647943, ENST00000648275, ENST00000657871, ENST00000739872, ENST00000739873, ENST00000739874, ENST00000739875, ENST00000739876, ENST00000739877, ENST00000739878, ENST00000739879, ENST00000739880, ENST00000792594, ENST00000792595, ENST00000792596, ENST00000792597, ENST00000792598, ENST00000792599

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439421 — 2 exons

Exon	Start	End
ENSE00001684820	130439067	130439089
ENSE00001755581	130482881	130483154

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 89.01.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0253 / max 12.6304, expressed in 10 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
107683	0.0253	10

Top tissues by expression

93 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.01	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.39	gold quality
right testis	UBERON:0004534	70.99	gold quality
left testis	UBERON:0004533	70.62	gold quality
testis	UBERON:0000473	70.19	gold quality
colonic epithelium	UBERON:0000397	65.76	silver quality
hindlimb stylopod muscle	UBERON:0004252	62.56	gold quality
skeletal muscle tissue	UBERON:0001134	61.35	gold quality
duodenum	UBERON:0002114	61.10	gold quality
prefrontal cortex	UBERON:0000451	56.62	gold quality
monocyte	CL:0000576	53.63	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.23	gold quality
amygdala	UBERON:0001876	52.15	gold quality
multicellular organism	UBERON:0000468	50.31	gold quality
blood	UBERON:0000178	50.28	gold quality
frontal cortex	UBERON:0001870	49.81	gold quality
Ammon’s horn	UBERON:0001954	49.68	gold quality
small intestine	UBERON:0002108	49.61	gold quality
muscle of leg	UBERON:0001383	49.51	gold quality
anterior cingulate cortex	UBERON:0009835	49.44	gold quality
cerebral cortex	UBERON:0000956	49.28	gold quality
Brodmann (1909) area 9	UBERON:0013540	49.25	gold quality
popliteal artery	UBERON:0002250	48.75	gold quality
gastrocnemius	UBERON:0001388	48.67	gold quality
kidney	UBERON:0002113	48.56	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	48.45	gold quality
tibial artery	UBERON:0007610	48.39	gold quality
substantia nigra	UBERON:0002038	48.25	gold quality
left coronary artery	UBERON:0001626	48.09	gold quality
metanephros cortex	UBERON:0010533	48.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.