LINC02649

Summary

LINC02649 (long intergenic non-protein coding RNA 2649, HGNC:54134) is a long non-coding RNA gene on chromosome 10p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54134
Approved symbol	LINC02649
Name	long intergenic non-protein coding RNA 2649
Location	10p15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000215244
Ensembl biotype	lncRNA
Entrez	399715
RNAcentral	URS000075AE77 — lncRNA, 2967 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000399868, ENST00000659311, ENST00000660179, ENST00000664595, ENST00000670319, ENST00000670683, ENST00000689295, ENST00000783921, ENST00000783922, ENST00000783923, ENST00000783924, ENST00000783925, ENST00000783926, ENST00000783927, ENST00000783928, ENST00000783929, ENST00000783930, ENST00000783931, ENST00000783932

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000399868 — 7 exons

Exon	Start	End
ENSE00001540513	6335257	6335982
ENSE00001540514	6331501	6331603
ENSE00001540516	6331211	6331306
ENSE00001540517	6330953	6331016
ENSE00001540518	6327932	6329810
ENSE00001540519	6326546	6326642
ENSE00001540521	6277687	6277807

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 81.13.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1510 / max 14.3536, expressed in 67 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
103694	0.1510	67

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	81.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.49	gold quality
right uterine tube	UBERON:0001302	77.31	gold quality
corpus callosum	UBERON:0002336	76.88	gold quality
colonic epithelium	UBERON:0000397	75.49	gold quality
bone marrow cell	CL:0002092	74.49	gold quality
descending thoracic aorta	UBERON:0002345	69.80	gold quality
bone marrow	UBERON:0002371	69.80	gold quality
ventricular zone	UBERON:0003053	69.37	gold quality
ascending aorta	UBERON:0001496	67.99	gold quality
thoracic aorta	UBERON:0001515	67.81	gold quality
lower esophagus mucosa	UBERON:0035834	67.43	gold quality
caudate nucleus	UBERON:0001873	67.21	gold quality
metanephros cortex	UBERON:0010533	67.00	gold quality
skeletal muscle tissue	UBERON:0001134	66.80	gold quality
spleen	UBERON:0002106	66.07	gold quality
tonsil	UBERON:0002372	65.67	gold quality
nucleus accumbens	UBERON:0001882	65.23	gold quality
putamen	UBERON:0001874	65.22	gold quality
amygdala	UBERON:0001876	64.74	gold quality
temporal lobe	UBERON:0001871	64.61	gold quality
Ammon’s horn	UBERON:0001954	64.56	gold quality
substantia nigra	UBERON:0002038	64.28	gold quality
urinary bladder	UBERON:0001255	64.23	gold quality
stromal cell of endometrium	CL:0002255	64.05	gold quality
gall bladder	UBERON:0002110	64.03	gold quality
muscle tissue	UBERON:0002385	63.85	gold quality
fallopian tube	UBERON:0003889	63.84	gold quality
ovary	UBERON:0000992	63.79	gold quality
uterine cervix	UBERON:0000002	63.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.41

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.