LINC02653

Summary

LINC02653 (long intergenic non-protein coding RNA 2653, HGNC:54138) is a long non-coding RNA gene on chromosome 10q23.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54138
Approved symbol	LINC02653
Name	long intergenic non-protein coding RNA 2653
Location	10q23.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236373
Ensembl biotype	lncRNA
Entrez	101926942
RNAcentral	URS000037889D — lncRNA, 981 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000418379, ENST00000660339

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418379 — 7 exons

Exon	Start	End
ENSE00001599884	90406450	90406595
ENSE00001652205	90527274	90527439
ENSE00001690974	90403988	90404054
ENSE00001714227	90402521	90402808
ENSE00001720672	90540732	90540805
ENSE00001767921	90451680	90451833
ENSE00001796723	90402954	90403039

Expression profiles

Bgee: expression breadth broad, 35 present calls, max score 81.88.

Top tissues by expression

35 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.88	silver quality
corpus callosum	UBERON:0002336	60.27	gold quality
blood	UBERON:0000178	53.15	silver quality
monocyte	CL:0000576	51.38	gold quality
prefrontal cortex	UBERON:0000451	50.64	gold quality
calcaneal tendon	UBERON:0003701	49.43	silver quality
muscle of leg	UBERON:0001383	46.28	silver quality
frontal cortex	UBERON:0001870	45.65	gold quality
superior frontal gyrus	UBERON:0002661	45.29	silver quality
gastrocnemius	UBERON:0001388	45.03	silver quality
Brodmann (1909) area 9	UBERON:0013540	44.31	silver quality
small intestine	UBERON:0002108	44.14	silver quality
islet of Langerhans	UBERON:0000006	42.56	silver quality
body of stomach	UBERON:0001161	42.33	silver quality
ascending aorta	UBERON:0001496	42.12	silver quality
thoracic aorta	UBERON:0001515	42.01	silver quality
skin of leg	UBERON:0001511	41.38	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	40.86	silver quality
esophagus mucosa	UBERON:0002469	40.74	silver quality
anterior cingulate cortex	UBERON:0009835	40.71	silver quality
stomach	UBERON:0000945	40.50	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	39.70	silver quality
lower esophagus muscularis layer	UBERON:0035833	38.91	silver quality
minor salivary gland	UBERON:0001830	38.82	silver quality
amygdala	UBERON:0001876	38.15	silver quality
substantia nigra	UBERON:0002038	38.02	silver quality
putamen	UBERON:0001874	37.76	silver quality
thyroid gland	UBERON:0002046	37.66	silver quality
Ammon’s horn	UBERON:0001954	35.69	silver quality
muscle layer of sigmoid colon	UBERON:0035805	35.32	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.