LINC02663
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Summary
LINC02663 (long intergenic non-protein coding RNA 2663, HGNC:54149) is a long non-coding RNA gene on chromosome 10p14.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:54149 |
| Approved symbol | LINC02663 |
| Name | long intergenic non-protein coding RNA 2663 |
| Location | 10p14 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000228636 |
| Ensembl biotype | lncRNA |
| Entrez | 105376402 |
| RNAcentral | URS0002A56337 — lncRNA, 1571 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 6 — 6 lncRNA
ENST00000419836, ENST00000647601, ENST00000659451, ENST00000840890, ENST00000840891, ENST00000840892
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000419836 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001606593 | 9759079 | 9759237 |
| ENSE00001764695 | 9758783 | 9758967 |
Expression profiles
Bgee: expression breadth broad, 86 present calls, max score 93.57.
FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1306 / max 53.2280, expressed in 36 samples.
FANTOM5 promoters (2 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 108226 | 0.0916 | 36 |
| 108225 | 0.0390 | 3 |
Top tissues by expression
86 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| left testis | UBERON:0004533 | 93.57 | gold quality |
| right testis | UBERON:0004534 | 93.37 | gold quality |
| testis | UBERON:0000473 | 92.52 | gold quality |
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 89.10 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 84.90 | gold quality |
| bone marrow cell | CL:0002092 | 78.22 | gold quality |
| right adrenal gland cortex | UBERON:0035827 | 61.56 | gold quality |
| gall bladder | UBERON:0002110 | 60.75 | gold quality |
| multicellular organism | UBERON:0000468 | 59.55 | gold quality |
| monocyte | CL:0000576 | 58.34 | gold quality |
| islet of Langerhans | UBERON:0000006 | 56.73 | gold quality |
| blood | UBERON:0000178 | 55.90 | gold quality |
| prefrontal cortex | UBERON:0000451 | 55.51 | gold quality |
| muscle of leg | UBERON:0001383 | 54.08 | gold quality |
| gastrocnemius | UBERON:0001388 | 53.77 | gold quality |
| duodenum | UBERON:0002114 | 53.44 | gold quality |
| placenta | UBERON:0001987 | 53.06 | gold quality |
| heart left ventricle | UBERON:0002084 | 52.60 | gold quality |
| left adrenal gland | UBERON:0001234 | 52.54 | gold quality |
| body of pancreas | UBERON:0001150 | 50.56 | gold quality |
| body of stomach | UBERON:0001161 | 49.36 | gold quality |
| liver | UBERON:0002107 | 49.36 | gold quality |
| stomach | UBERON:0000945 | 49.28 | gold quality |
| ascending aorta | UBERON:0001496 | 48.51 | gold quality |
| thoracic aorta | UBERON:0001515 | 48.43 | gold quality |
| tonsil | UBERON:0002372 | 48.28 | gold quality |
| tibial artery | UBERON:0007610 | 48.28 | gold quality |
| muscle layer of sigmoid colon | UBERON:0035805 | 48.12 | gold quality |
| corpus callosum | UBERON:0002336 | 48.02 | silver quality |
| lower esophagus muscularis layer | UBERON:0035833 | 47.70 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 1.62 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): alcoholic liver cirrhosis