LINC02677

Summary

LINC02677 (long intergenic non-protein coding RNA 2677, HGNC:54171) is a long non-coding RNA gene on chromosome 10p15.1.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54171
Approved symbol	LINC02677
Name	long intergenic non-protein coding RNA 2677
Location	10p15.1
Locus type	RNA, long non-coding
Status	Approved
Entrez	102723629
RNAcentral	URS00026A229B — lncRNA, 948 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000595685 (10:5618760 C>A,T), RS1002038499 (10:5618363 G>A), RS1003175481 (10:5617652 A>G), RS1004027715 (10:5619305 C>T), RS1004676414 (10:5619616 T>C), RS1007078802 (10:5617814 G>T), RS1007349819 (10:5617686 A>G), RS1007942250 (10:5616224 G>A,T), RS1008219490 (10:5619850 G>A,C), RS1009392788 (10:5618389 G>A,C), RS1010223258 (10:5617165 C>T), RS1011457665 (10:5616706 C>G), RS1011947315 (10:5616186 C>T), RS1012035546 (10:5617342 C>A,T), RS1012311208 (10:5617112 G>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
sodium arsenite	decreases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.