LINC02722

Summary

LINC02722 (long intergenic non-protein coding RNA 2722, HGNC:54239) is a long non-coding RNA gene on chromosome 11p13.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54239
Approved symbol	LINC02722
Name	long intergenic non-protein coding RNA 2722
Location	11p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255169
Entrez	105376619
RNAcentral	URS00026A25BA — lncRNA, 586 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Bgee: expression breadth broad, 50 present calls, max score 67.50.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0257 / max 19.2275, expressed in 5 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
113693	0.0193	3
206245	0.0064	2

Top tissues by expression

50 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	67.50	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.47	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.91	gold quality
blood	UBERON:0000178	55.67	gold quality
prostate gland	UBERON:0002367	54.37	gold quality
right testis	UBERON:0004534	54.37	gold quality
left testis	UBERON:0004533	54.08	gold quality
lung	UBERON:0002048	53.29	gold quality
testis	UBERON:0000473	53.22	gold quality
monocyte	CL:0000576	52.99	silver quality
ovary	UBERON:0000992	52.90	gold quality
vermiform appendix	UBERON:0001154	51.51	gold quality
endometrium	UBERON:0001295	50.08	gold quality
islet of Langerhans	UBERON:0000006	49.78	gold quality
prefrontal cortex	UBERON:0000451	49.24	gold quality
cortex of kidney	UBERON:0001225	49.15	silver quality
body of uterus	UBERON:0009853	46.24	gold quality
gastrocnemius	UBERON:0001388	45.69	gold quality
spleen	UBERON:0002106	45.45	gold quality
urinary bladder	UBERON:0001255	44.66	silver quality
myometrium	UBERON:0001296	44.23	gold quality
vagina	UBERON:0000996	44.04	gold quality
left coronary artery	UBERON:0001626	43.82	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	43.74	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	43.61	gold quality
lower esophagus mucosa	UBERON:0035834	43.28	silver quality
muscle layer of sigmoid colon	UBERON:0035805	43.11	gold quality
rectum	UBERON:0001052	42.82	gold quality
colon	UBERON:0001155	42.53	gold quality
esophagus mucosa	UBERON:0002469	42.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000094514 (11:33805424 C>A,T), RS1000212905 (11:33809087 C>T), RS1000703690 (11:33803701 A>T), RS1001589823 (11:33808212 T>C), RS1002474758 (11:33803758 C>A,T), RS1002700692 (11:33806964 C>T), RS1003112472 (11:33806690 A>T), RS1003553270 (11:33806942 T>C), RS1003859143 (11:33805216 G>A,T), RS1004069310 (11:33805932 A>C,T), RS1004504381 (11:33806290 A>G), RS1004985968 (11:33806051 T>C,G), RS1005362937 (11:33805768 T>A), RS1006385395 (11:33807226 G>A,T), RS1006586184 (11:33803733 G>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.