LINC02725

Summary

LINC02725 (long intergenic non-protein coding RNA 2725, HGNC:54242) is a long non-coding RNA gene on chromosome 11q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54242
Approved symbol	LINC02725
Name	long intergenic non-protein coding RNA 2725
Location	11q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000273415
Ensembl biotype	lncRNA
Entrez	105369563
RNAcentral	URS00026A2259 — lncRNA, 1622 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000609911, ENST00000649115, ENST00000654938, ENST00000664091, ENST00000665260, ENST00000670942, ENST00000671140, ENST00000783503, ENST00000783504

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000609911 — 2 exons

Exon	Start	End
ENSE00003707415	128180427	128180623
ENSE00003711019	128182801	128183554

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 76.07.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3946 / max 219.4807, expressed in 62 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
117531	0.1613	41
117536	0.0784	17
117535	0.0500	11
117538	0.0409	12
117533	0.0194	5
117534	0.0168	6
117537	0.0163	5
117532	0.0114	6

Top tissues by expression

95 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	76.07	gold quality
skeletal muscle tissue	UBERON:0001134	61.65	silver quality
ascending aorta	UBERON:0001496	60.17	gold quality
calcaneal tendon	UBERON:0003701	60.00	gold quality
thoracic aorta	UBERON:0001515	59.68	gold quality
duodenum	UBERON:0002114	55.34	gold quality
granulocyte	CL:0000094	55.32	gold quality
leukocyte	CL:0000738	54.91	silver quality
smooth muscle tissue	UBERON:0001135	54.38	gold quality
urinary bladder	UBERON:0001255	54.24	gold quality
prefrontal cortex	UBERON:0000451	53.49	gold quality
blood	UBERON:0000178	53.09	gold quality
tibial artery	UBERON:0007610	52.94	gold quality
popliteal artery	UBERON:0002250	52.79	gold quality
lymph node	UBERON:0000029	52.49	gold quality
metanephros cortex	UBERON:0010533	52.44	gold quality
monocyte	CL:0000576	52.28	silver quality
stromal cell of endometrium	CL:0002255	52.14	silver quality
placenta	UBERON:0001987	50.62	gold quality
cortex of kidney	UBERON:0001225	50.15	gold quality
gall bladder	UBERON:0002110	50.10	gold quality
descending thoracic aorta	UBERON:0002345	49.40	gold quality
kidney	UBERON:0002113	48.88	gold quality
liver	UBERON:0002107	48.61	silver quality
superior frontal gyrus	UBERON:0002661	48.54	gold quality
bone marrow	UBERON:0002371	48.19	silver quality
right atrium auricular region	UBERON:0006631	48.09	gold quality
muscle of leg	UBERON:0001383	48.01	gold quality
Brodmann (1909) area 9	UBERON:0013540	47.79	gold quality
multicellular organism	UBERON:0000468	47.64	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.42

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.