LINC02727

Summary

LINC02727 (long intergenic non-protein coding RNA 2727, HGNC:54244) is a long non-coding RNA gene on chromosome 11q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54244
Approved symbol	LINC02727
Name	long intergenic non-protein coding RNA 2727
Location	11q24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254823
Ensembl biotype	lncRNA
Entrez	105369541
RNAcentral	URS00026A2462 — lncRNA, 449 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000527533, ENST00000527774, ENST00000657363, ENST00000657507, ENST00000664077, ENST00000729378, ENST00000729379, ENST00000729380, ENST00000729381

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000527533 — 2 exons

Exon	Start	End
ENSE00002159063	123313674	123313793
ENSE00002201131	123314503	123314770

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 97.74.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0266 / max 20.7499, expressed in 3 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
122898	0.0170	3
122900	0.0052	3
122899	0.0044	3

Top tissues by expression

188 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	97.74	gold quality
left testis	UBERON:0004533	87.26	gold quality
sural nerve	UBERON:0015488	87.06	gold quality
right testis	UBERON:0004534	86.36	gold quality
testis	UBERON:0000473	83.49	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.77	gold quality
pancreatic ductal cell	CL:0002079	72.20	silver quality
colonic epithelium	UBERON:0000397	70.42	gold quality
ventricular zone	UBERON:0003053	61.74	gold quality
secondary oocyte	CL:0000655	59.18	gold quality
tibialis anterior	UBERON:0001385	58.31	silver quality
ganglionic eminence	UBERON:0004023	56.83	gold quality
epithelial cell of pancreas	CL:0000083	56.13	gold quality
vena cava	UBERON:0004087	54.73	gold quality
deltoid	UBERON:0001476	54.54	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
lateral nuclear group of thalamus	UBERON:0002736	54.09	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
bone marrow	UBERON:0002371	52.71	gold quality
adult organism	UBERON:0007023	51.92	silver quality
buccal mucosa cell	CL:0002336	51.27	gold quality
muscle of leg	UBERON:0001383	51.21	gold quality
trabecular bone tissue	UBERON:0002483	50.63	gold quality
myocardium	UBERON:0002349	50.25	gold quality
gastrocnemius	UBERON:0001388	49.98	gold quality
cardiac atrium	UBERON:0002081	49.34	gold quality
quadriceps femoris	UBERON:0001377	49.13	gold quality
ileal mucosa	UBERON:0000331	49.07	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.