LINC02728

Summary

LINC02728 (long intergenic non-protein coding RNA 2728, HGNC:54245) is a long non-coding RNA gene on chromosome 11q14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54245
Approved symbol	LINC02728
Name	long intergenic non-protein coding RNA 2728
Location	11q14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251323
Ensembl biotype	lncRNA
Entrez	101928865
RNAcentral	URS000075ED9D — lncRNA, 1654 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000513207, ENST00000660634, ENST00000664831, ENST00000841774

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000513207 — 4 exons

Exon	Start	End
ENSE00002020056	78429700	78429836
ENSE00002065509	78427309	78427530
ENSE00002075347	78425337	78425405
ENSE00002083399	78423982	78425195

Expression profiles

Bgee: expression breadth ubiquitous, 152 present calls, max score 81.70.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.7275 / max 87.9975, expressed in 149 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
121505	0.5084	100
121504	0.0870	41
121508	0.0832	19
121509	0.0284	12
121506	0.0124	5
121507	0.0081	6

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.70	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.64	gold quality
bone marrow cell	CL:0002092	72.24	gold quality
granulocyte	CL:0000094	71.22	gold quality
colonic epithelium	UBERON:0000397	69.19	silver quality
monocyte	CL:0000576	66.52	gold quality
calcaneal tendon	UBERON:0003701	66.06	gold quality
mucosa of stomach	UBERON:0001199	65.82	gold quality
sural nerve	UBERON:0015488	64.81	silver quality
body of pancreas	UBERON:0001150	64.79	gold quality
left uterine tube	UBERON:0001303	62.73	gold quality
skin of leg	UBERON:0001511	62.61	gold quality
right ovary	UBERON:0002118	62.45	gold quality
ventricular zone	UBERON:0003053	62.10	gold quality
skin of abdomen	UBERON:0001416	61.45	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.02	gold quality
left ovary	UBERON:0002119	60.65	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.53	gold quality
pancreas	UBERON:0001264	60.13	gold quality
ectocervix	UBERON:0012249	60.11	gold quality
buccal mucosa cell	CL:0002336	59.86	gold quality
lower lobe of lung	UBERON:0008949	59.61	silver quality
zone of skin	UBERON:0000014	59.54	gold quality
right uterine tube	UBERON:0001302	59.19	gold quality
ovary	UBERON:0000992	58.93	gold quality
cortical plate	UBERON:0005343	58.79	gold quality
body of uterus	UBERON:0009853	58.45	gold quality
subcutaneous adipose tissue	UBERON:0002190	58.10	gold quality
upper lobe of lung	UBERON:0008948	58.03	gold quality
upper lobe of left lung	UBERON:0008952	57.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.