LINC02731

Summary

LINC02731 (long intergenic non-protein coding RNA 2731, HGNC:54248) is a long non-coding RNA gene on chromosome 11q25.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54248
Approved symbol	LINC02731
Name	long intergenic non-protein coding RNA 2731
Location	11q25
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000204241
Ensembl biotype	lncRNA
Entrez	100128239
RNAcentral	URS000075EF0C — lncRNA, 2299 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000527712, ENST00000529070, ENST00000531938, ENST00000532327, ENST00000532706, ENST00000533091, ENST00000533922, ENST00000655895, ENST00000662392, ENST00000662879, ENST00000687703, ENST00000810748, ENST00000810749, ENST00000810750, ENST00000810751, ENST00000810752, ENST00000810753, ENST00000810754, ENST00000810755, ENST00000810756

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000527712 — 5 exons

Exon	Start	End
ENSE00001464608	134037512	134037641
ENSE00002166711	134039762	134040080
ENSE00003853315	134046761	134046945
ENSE00003923124	134032681	134032860
ENSE00003937565	134047637	134048058

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 82.91.

FANTOM5 (CAGE): breadth broad, TPM avg 1.5884 / max 290.3580, expressed in 280 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
117689	0.6378	46
117684	0.3385	120
117687	0.1993	102
117688	0.1433	41
117690	0.1108	35
117686	0.0669	20
117685	0.0526	20
117683	0.0391	11

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	82.91	gold quality
cerebellar hemisphere	UBERON:0002245	82.72	gold quality
cerebellar cortex	UBERON:0002129	82.69	gold quality
cerebellum	UBERON:0002037	81.33	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.51	gold quality
anterior cingulate cortex	UBERON:0009835	74.80	gold quality
right frontal lobe	UBERON:0002810	73.55	gold quality
hypothalamus	UBERON:0001898	72.99	gold quality
cerebellar vermis	UBERON:0004720	72.96	gold quality
Brodmann (1909) area 9	UBERON:0013540	72.19	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	70.91	gold quality
prefrontal cortex	UBERON:0000451	70.83	gold quality
amygdala	UBERON:0001876	69.79	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.53	gold quality
neocortex	UBERON:0001950	69.48	gold quality
putamen	UBERON:0001874	68.53	gold quality
frontal cortex	UBERON:0001870	68.52	gold quality
spinal cord	UBERON:0002240	68.34	gold quality
nucleus accumbens	UBERON:0001882	68.28	gold quality
caudate nucleus	UBERON:0001873	67.51	gold quality
brain	UBERON:0000955	67.50	gold quality
cerebral cortex	UBERON:0000956	66.99	gold quality
sural nerve	UBERON:0015488	66.71	gold quality
substantia nigra	UBERON:0002038	66.49	gold quality
primary visual cortex	UBERON:0002436	66.49	gold quality
stromal cell of endometrium	CL:0002255	66.20	gold quality
cortical plate	UBERON:0005343	66.14	gold quality
forebrain	UBERON:0001890	66.12	gold quality
colonic epithelium	UBERON:0000397	66.07	silver quality
ventricular zone	UBERON:0003053	65.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.90

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.